Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | TRAP1 | Q12931 | 7/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.36 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | HSP90B1 | P14625 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26923080 | 0.84 | HSP90AA1 (0.40) | NOTUMTRAP1DPP8DPP9DPP7 | |
| SCHEMBL20310026 | 0.83 | NOTUM (0.37) | NOTUMTRAP1DPP8DPP9DPP7 | |
| SCHEMBL7946982 | 0.78 | TRAP1 (0.52) | NOTUMTRAP1DPP8DPP9DPP7 | |
| SCHEMBL13284584 | 0.77 | NAMPT (0.35) | DPP8DPP9DPP7NAMPTMEN1 | |
| SCHEMBL28838781 | 0.76 | LMNA (0.51) | — | |
| SCHEMBL16637906 | 0.75 | TRAP1 (0.43) | NOTUMTRAP1ABHD6HSP90B1 | |
| SCHEMBL13284596 | 0.74 | HSP90AA1 (0.33) | DPP8DPP9DPP7ABHD6 | |
| SCHEMBL13284260 | 0.74 | LMNA (0.36) | DPP8DPP9DPP7NAMPTHPGD | |
| SCHEMBL28245906 | 0.74 | MAPT (0.43) | NOTUMABHD6MAPTMEN1KMT2A | |
| SCHEMBL28246667 | 0.74 | MAPT (0.43) | NOTUMABHD6MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010080389-A1 | HCV NS3 PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2010-07-15 | — | — | WO | disclosed |