Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 3/20 | 0.35 |
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.34 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.34 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10059459 | 0.89 | GAA (0.48) | DRD4DRD2DRD3GAANPC1 | |
| SCHEMBL13075035 | 0.81 | HSD17B10 (0.53) | GAANPC1NOX4 | |
| SCHEMBL13284320 | 0.80 | GAA (0.37) | GAAMAPTNOX4 | |
| SCHEMBL13284152 | 0.77 | ALDH1A1 (0.39) | GAANPC1MAPTBRD4NOX4 | |
| SCHEMBL13284148 | 0.77 | F10 (0.42) | GAAMAPTNOX4 | |
| SCHEMBL13075262 | 0.76 | CNR1 (0.38) | GAANOX4 | |
| SCHEMBL13580369 | 0.75 | CYP17A1 (0.40) | MAPT | |
| SCHEMBL13284149 | 0.74 | ACSS2 (0.38) | — | |
| SCHEMBL13284321 | 0.73 | BRD4 (0.45) | BRD4 | |
| SCHEMBL10059490 | 0.73 | KDM4E (0.53) | DRD4DRD2DRD3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010085805-A1 | METHODS FOR TREATING ACUTE MYOCARDIAL INFARCTIONS AND ASSOCIATED DISORDERS | INTERMUNE, INC. (US) | 2010-07-29 | — | — | WO | disclosed |