Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | THPO | P40225 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6950016 | 0.91 | ALOX15 (0.50) | ALOX15KDM4EMAPTALDH1A1ADORA3 | |
| SCHEMBL6947901 | 0.88 | CYP2C9 (0.59) | ALOX15CYP2C9MEN1CYP1A2CYP3A4 | |
| SCHEMBL6949620 | 0.88 | CACNA1C (0.55) | CYP2C9MEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL6947853 | 0.87 | ALOX15 (0.59) | ALOX15CYP2C9MEN1CYP1A2CYP3A4 | |
| SCHEMBL9235442 | 0.87 | CACNA1B (0.46) | CYP2C9MEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8913648 | 0.86 | ADORA3 (0.52) | CYP2C9MEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL6953510 | 0.85 | SMN1; SMN2 (0.56) | ALOX15CYP2C9MEN1CYP1A2CYP3A4 | |
| SCHEMBL6953639 | 0.85 | GAA (0.45) | CYP2C9MEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL6948567 | 0.84 | SMN1; SMN2 (0.57) | ALOX15MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL3032439 | 0.84 | MTOR (0.59) | CYP2C9MEN1CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657432-B1 | Phenyl-substituted 1,4-dihydropyridines with cerebral activity | BAYER AG (DE) | 2003-03-12 | — | — | EP | claimed |