SCHEMBL1328526

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1327948	0.93	TAS1R3 (0.48)	MCHR1ADRA2AHTR2BHRH1DPP4
	SCHEMBL1327152	0.89	ADRA2A (0.54)	MCHR1ADRA2AHTR2BHRH1DPP4
	SCHEMBL1326528	0.89	NPC1 (0.56)	MCHR1ADRA2AHTR2BHRH1KDM4E
	SCHEMBL2310236	0.89	ADRA2A (0.46)	MCHR1ADRA2AHTR2BHRH1DPP4
	SCHEMBL1327192	0.82	HTR2B (0.48)	MCHR1ADRA2AHTR2BKDM4EMEN1
	SCHEMBL27751619	0.82	HPGD (0.51)	MEN1MAPTKMT2AHPGDNPC1
	SCHEMBL1327179	0.82	TAS1R3 (0.46)	MCHR1ADRA2ADPP4DPP7MEN1
	SCHEMBL1327913	0.79	HPGD (0.46)	MCHR1HTR2BDPP4DPP7HPGD
	SCHEMBL644813	0.78	L3MBTL1 (0.41)	MEN1POLBKMT2AHPGDRAB9A
	SCHEMBL644812	0.77	L3MBTL1 (0.43)	KDM4EMEN1POLBMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.