Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL792258 | 0.88 | L3MBTL1 (0.41) | ALDH1A1PDE4DFFAR1 | |
| SCHEMBL13286249 | 0.82 | CHEK2 (0.39) | — | |
| SCHEMBL13285967 | 0.80 | ROCK2 (0.40) | ALDH1A1 | |
| SCHEMBL13286176 | 0.80 | PLK1 (0.39) | HSD17B1 | |
| SCHEMBL13285969 | 0.79 | ROCK2 (0.36) | ALDH1A1EGFR | |
| SCHEMBL13286175 | 0.78 | HSP90AA1 (0.48) | ALDH1A1 | |
| SCHEMBL13285984 | 0.78 | CA12 (0.39) | EGFR | |
| SCHEMBL13286262 | 0.77 | PDK2 (0.40) | SRD5A2HSD17B1 | |
| SCHEMBL13286177 | 0.77 | HPGD (0.44) | ALDH1A1 | |
| SCHEMBL13285889 | 0.76 | KMT2A (0.48) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206715-A1 | Fused heterotetracyclic compounds and use thereof as hcv polymerase inhibitor | Japan Tobacco, Inc. (JP) | 2010-07-14 | — | — | EP | disclosed |