Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CCR3 | P51677 | 3/20 | 0.35 |
| ▸ | RHEB | Q15382 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL771703 | 0.89 | CNR2 (0.41) | PRKCAMMP12HDAC1HDAC8HDAC6 | |
| SCHEMBL793031 | 0.85 | ALDH1A1 (0.36) | NPC1RAB9AKMT2ACCR3ALDH1A1 | |
| SCHEMBL13286194 | 0.83 | MEN1 (0.36) | PRKCAMMP12HDAC1HDAC8HDAC6 | |
| SCHEMBL6368385 | 0.77 | SCN9A (0.42) | HDAC1HDAC8HDAC6SCN9ADRD3 | |
| SCHEMBL13095926 | 0.75 | PRKCA (0.41) | PRKCAMMP12CCR3RHEBSCN9A | |
| SCHEMBL1173428 | 0.73 | ALDH1A1 (0.44) | HDAC1HDAC8HDAC6ALDH1A1HPGD | |
| SCHEMBL5755299 | 0.73 | PRKCA (0.44) | PRKCAMMP12HDAC1HDAC8HDAC6 | |
| SCHEMBL5300454 | 0.73 | PRKCA (0.40) | PRKCAMMP12HDAC1HDAC8HDAC6 | |
| SCHEMBL771509 | 0.73 | ALDH1A1 (0.44) | HDAC1HDAC8HDAC6NPC1KMT2A | |
| SCHEMBL14263679 | 0.72 | SCN9A (0.36) | PRKCAMMP12HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206715-A1 | Fused heterotetracyclic compounds and use thereof as hcv polymerase inhibitor | Japan Tobacco, Inc. (JP) | 2010-07-14 | — | — | EP | disclosed |