Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | ALB | P02768 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | TK1 | P04183 | 7/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920703 | 1.00 | LMNA (0.58) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL27505365 | 1.00 | LMNA (0.58) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL23485 | 1.00 | LMNA (0.58) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL14596607 | 1.00 | LMNA (0.58) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL925743 | 1.00 | LMNA (0.58) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL29711774 | 1.00 | LMNA (0.58) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL14421795 | 1.00 | LMNA (0.58) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL762579 | 1.00 | LMNA (0.58) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL22992337 | 1.00 | LMNA (0.58) | LMNAALBBLMALDH1A1POLB | |
| Methane SCHEMBL25262791 | 0.99 | TK1 (0.57) | LMNAALBBLMALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4234566-A1 | MODIFIED NUCLEOSIDE OR NUCLEOTIDE | BGI Shenzhen (CN) | 2023-08-30 | — | — | EP | disclosed |
| WO-2022125984-A1 | TAU-TARGETING OLIGONUCLEOTIDE GAPMERS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2022-06-16 | — | — | WO | disclosed |
| EP-2742136-B1 | GAPPED OLIGOMERIC COMPOUNDS COMPRISING 5'-MODIFIED DEOXYRIBONUCLEOSIDES IN THE GAP AND USES THEREOF | IONIS PHARMACEUTICALS INC (US) | 2017-09-27 | — | — | EP | disclosed |
| WO-2010072831-A1 | SULFURIZING REAGENTS AND THEIR USE FOR OLIGONUCLEOTIDES SYNTHESIS | GIRINDUS AMERICA, INC (US) | 2010-07-01 | — | — | WO | disclosed |