SCHEMBL762579

SCHEMBL762579

Cc1cn(C2CCC(CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.63

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.58
ALB P02768 2/20 0.58
BLM P54132 2/20 0.58
ALDH1A1 P00352 1/20 0.58
POLB P06746 1/20 0.58
ADRA1A P35348 1/20 0.58
TK1 P04183 7/20 0.58
TSHR P16473 2/20 0.58
PKM P14618 1/20 0.58
PMP22 Q01453 1/20 0.58
CYP2D6 P10635 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8920703 1.00 LMNA (0.58) LMNAALBBLMALDH1A1POLB
SCHEMBL13286394 1.00 LMNA (0.58) LMNAALBBLMALDH1A1POLB
SCHEMBL27505365 1.00 LMNA (0.58) LMNAALBBLMALDH1A1POLB
SCHEMBL23485 1.00 LMNA (0.58) LMNAALBBLMALDH1A1POLB
SCHEMBL14596607 1.00 LMNA (0.58) LMNAALBBLMALDH1A1POLB
SCHEMBL925743 1.00 LMNA (0.58) LMNAALBBLMALDH1A1POLB
SCHEMBL29711774 1.00 LMNA (0.58) LMNAALBBLMALDH1A1POLB
SCHEMBL14421795 1.00 LMNA (0.58) LMNAALBBLMALDH1A1POLB
SCHEMBL22992337 1.00 LMNA (0.58) LMNAALBBLMALDH1A1POLB
Methane SCHEMBL25262791 0.99 TK1 (0.57) LMNAALBBLMALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024129985-A2 ANTIVIRAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF Lakewood Amedex, Inc. (US) 2024-06-20 WO disclosed
EP-4234566-A1 MODIFIED NUCLEOSIDE OR NUCLEOTIDE BGI Shenzhen (CN) 2023-08-30 EP disclosed
WO-2023113038-A1 OLIGONUCLEOTIDE PRODUCTION METHOD リードファーマ株式会社 2023-06-22 WO disclosed
WO-2023086557-A1 NUCLEOSIDES FOR THE TREATMENT OF DNA VIRUS INFECTIONS EMORY UNIVERSITY (US) 2023-05-19 WO disclosed
WO-2023004130-A1 METHODS FOR PREPARING BISPHOSPHOCINS Lakewood Amedex, Inc. (US) 2023-01-26 WO disclosed
US-20220195437-A1 TAU-TARGETING OLIGONUCLEOTIDE GAPMERS EISAI R&D MANAGEMENT CO., LTD. (JP) 2022-06-23 US disclosed
WO-2022125987-A1 POLY-MORPHOLINO OLIGONUCLEOTIDE GAPMERS EISAI R&D MANAGEMENT CO., LTD. (JP) 2022-06-16 WO disclosed
WO-2022125984-A1 TAU-TARGETING OLIGONUCLEOTIDE GAPMERS EISAI R&D MANAGEMENT CO., LTD. (JP) 2022-06-16 WO disclosed
WO-2022083686-A1 MODIFIED NUCLEOSIDE OR NUCLEOTIDE 深圳华大生命科学研究院 2022-04-28 WO disclosed
EP-3169693-B1 CHIMERIC POLYNUCLEOTIDES MODERNATX INC (US) 2022-03-09 EP disclosed
US-8137560-B2 Separation process GE HEALTHCARE LIMITED (GB) 2012-03-20 US disclosed
US-8137560-B2 Separation process GE HEALTHCARE LIMITED (GB) 2012-03-20 US disclosed
US-8022083-B2 Antiviral phosphonate analogs GILEAD SCIENCES, INC. (US) 2011-09-20 US disclosed
US-20100105888-A1 SEPARATION PROCESS GE HEALTHCARE LIMITED (GB) 2010-04-29 US disclosed
US-20100105888-A1 SEPARATION PROCESS GE HEALTHCARE LIMITED (GB) 2010-04-29 US disclosed
US-20090275535-A1 ANTIVIRAL PHOSPHONATE ANALOGS GILEAD SCIENCES, INC. 2009-11-05 US disclosed
US-7582748-B2 efficient synthetic route to an optionally protected 1-halo-2-deoxyribose; formation of an alkyl acetal, such as a methyl acetal, of a furanose, such as 2-deoxyribose, optionally protecting the remaining hydroxyl groups of the furanose, reacting the acetal with an acyl halide that forms the acid halide MICROBIOLOGICA QUIMICA E FARMACEUTICAL LTD. (BR) 2009-09-01 US disclosed
US-7429565-B2 Antiviral phosphonate analogs GILEAD SCIENCES, INC. (US) 2008-09-30 US disclosed
US-7172867-B2 Methods of testing for allergic diseases, and therapeutic agents for treating same GENOX RESEARCH, INC. (JP) 2007-02-06 US disclosed
US-7172867-B2 Methods of testing for allergic diseases, and therapeutic agents for treating same GENOX RESEARCH, INC. (JP) 2007-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090275535-A1 ANTIVIRAL PHOSPHONATE ANALOGS TYMP, ITPA, PNP LMNA 2918/4885ALB 2245/4885BLM 1162/4885
US-20100105888-A1 SEPARATION PROCESS PAICS, EPHX2, SAMHD1 LMNA 2414/4885ALB 4525/4885BLM 1177/4885
US-20220195437-A1 TAU-TARGETING OLIGONUCLEOTIDE GAPMERS MAPT, GAP43, RNMT LMNA 1392/4885ALB 4034/4885BLM 3835/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.