Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 3/20 | 0.39 |
| ▸ | REN | P00797 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14407891 | 0.92 | POLB (0.45) | POLBL3MBTL1ACERENF2 | |
| SCHEMBL14407812 | 0.85 | POLB (0.40) | POLBL3MBTL1ACERENF2 | |
| SCHEMBL2770743 | 0.84 | GPR84 (0.46) | MEN1KMT2AOPRD1 | |
| SCHEMBL2769589 | 0.84 | GPR84 (0.46) | MEN1KMT2AOPRD1 | |
| SCHEMBL14407896 | 0.84 | POLB (0.49) | POLBL3MBTL1ACERENF2 | |
| SCHEMBL14407813 | 0.82 | POLB (0.44) | POLBL3MBTL1ACERENNPC1 | |
| SCHEMBL14407893 | 0.81 | POLB (0.42) | POLBL3MBTL1MEN1KMT2AOPRD1 | |
| SCHEMBL24260264 | 0.79 | L3MBTL1 (0.50) | POLBL3MBTL1DPP4FAPDPP8 | |
| SCHEMBL14407901 | 0.79 | ALOX5 (0.47) | MEN1KMT2A | |
| SCHEMBL14407900 | 0.79 | ALOX5 (0.47) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745489-B2 | Compositions and methods for inhibition of phospholipase A2 mediated inflammation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-06-29 | — | — | US | disclosed |