Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CCR1 | P32246 | 4/20 | 0.52 |
| ▸ | CCR8 | P51685 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | CCR5 | P51681 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30022928 | 1.00 | DHFR (0.53) | DHFRHSP90AA1L3MBTL1NPC1CCR1 | |
| SCHEMBL31036114 | 0.91 | CCR1 (0.53) | DHFRHSP90AA1L3MBTL1NPC1CCR1 | |
| SCHEMBL912017 | 0.91 | CCR1 (0.53) | DHFRHSP90AA1L3MBTL1NPC1CCR1 | |
| SCHEMBL15672165 | 0.89 | DHFR (0.45) | DHFRHSP90AA1L3MBTL1NPC1CCR1 | |
| SCHEMBL30185055 | 0.88 | L3MBTL1 (0.54) | DHFRHSP90AA1L3MBTL1NPC1CCR1 | |
| SCHEMBL29390114 | 0.88 | L3MBTL1 (0.54) | DHFRHSP90AA1L3MBTL1NPC1CCR1 | |
| SCHEMBL30185058 | 0.88 | L3MBTL1 (0.54) | DHFRHSP90AA1L3MBTL1NPC1CCR1 | |
| SCHEMBL166826 | 0.88 | L3MBTL1 (0.54) | DHFRHSP90AA1L3MBTL1NPC1CCR1 | |
| Hydrochloric Acid SCHEMBL5931379 | 0.86 | L3MBTL1 (0.52) | DHFRHSP90AA1L3MBTL1NPC1CCR1 | |
| SCHEMBL6693951 | 0.86 | L3MBTL1 (0.52) | DHFRHSP90AA1L3MBTL1NPC1CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9816075-B2 | Compounds with modifying activity enhanced under hypoxic conditions | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-11-14 | — | — | US | disclosed |
| US-20150152390-A1 | Compounds With Modifying Activity Enhanced Under Hypoxic Conditions | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2015-06-04 | — | — | US | disclosed |
| US-8824048-B2 | Anisotropic dye layer, coordination polymer for anisotropic dye layer and polarization element, and polarization control film, polarization control element, multi-layer polarization control element, ellipse polarization plate, light emission element, and method for controlling polarization properties employing the anisotropic dye layer | KONICA MINOLTA OPTO, INC. (JP) | 2014-09-02 | — | — | US | disclosed |
| US-20130235552-A1 | ANISOTROPIC DYE LAYER, COORDINATION POLYMER FOR ANISOTROPIC DYE LAYER AND POLARIZATION ELEMENT, AND POLARIZATION CONTROL FILM, POLARIZATION CONTROL ELEMENT, MULTI-LAYER POLARIZATION CONTROL ELEMENT, ELLIPSE POLARIZATION PLATE, LIGHT EMISSION ELEMENT, AND METHOD FOR CONTROLLING POLARIZATION PROPERTIES EMPLOYING THE ANISOTROPIC DYE LAYER | KONICA MINOLTA OPTO, INC. (JP) | 2013-09-12 | — | — | US | disclosed |
| US-8472115-B2 | Anistropic dye layer, coordination polymer for anistropic dye layer and polarization element, and polarization control film, polarization control element, multi-layer polarization control element, ellipse polarization plate, light emission element, and method for controlling polarization properties employing the anistropic dye layer | KONICA MINOLTA OPTO, INC. (JP) | 2013-06-25 | — | — | US | disclosed |
| US-20120295880-A1 | Compounds With Modifying Activity Enhanced Under Hypoxic Conditions | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-11-22 | — | — | US | disclosed |
| US-20100142050-A1 | ANISTROPIC DYE LAYER, COORDINATION POLYMER FOR ANISTROPIC DYE LAYER AND POLARIZATION ELEMENT, AND POLARIZATION CONTROL FILM, POLARIZATION CONTROL ELEMENT, MULTI-LAYER POLARIZATION CONTROL ELEMENT, ELLIPSE POLARIZATION PLATE, LIGHT EMISSION ELEMENT, AND METHOD FOR CONTROLLING POLARIZATION PROPERTIES EMPLOYING THE ANISTROPIC DYE LAYER | KONICA MINOLTA OPTO, INC. (JP) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295880-A1 | Compounds With Modifying Activity Enhanced Under Hypoxic Conditions | HIF1A, HIF1AN, HYOU1 | DHFR 244/4885HSP90AA1 1772/4885L3MBTL1 3238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.