SCHEMBL132867

SCHEMBL132867

[CH2]CCCCCCCCCCCCC[CH]S(=O)(=O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR9 Q9NR96 1/20 0.42
ALDH1A1 P00352 7/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
MCOLN3 Q8TDD5 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
PKM P14618 1/20 0.38
HTR6 P50406 1/20 0.35
PSIP1 O75475 1/20 0.35
POLB P06746 1/20 0.35
TDP1 Q9NUW8 2/20 0.33
HSD17B10 Q99714 2/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5077216 0.82 EPHX2 (0.47) TLR9ALDH1A1PSIP1TDP1TSHR
SCHEMBL7330132 0.80 TDP1 (0.47) TLR9ALDH1A1SMN1; SMN2CYP1A2CYP2C9
SCHEMBL29171177 0.74 TDP1 (0.45) TLR9ALDH1A1SMN1; SMN2CYP1A2CYP2C9
SCHEMBL11868565 0.73 TLR9 (0.48) TLR9ALDH1A1SMN1; SMN2CYP1A2CYP2C9
SCHEMBL4394025 0.73 PSIP1 (0.50) TLR9ALDH1A1SMN1; SMN2CYP1A2CYP2C9
SCHEMBL7330137 0.72 HDAC1 (0.56) ALDH1A1SMN1; SMN2CYP2C9CYP2C19L3MBTL1
SCHEMBL5077217 0.72 HDAC1 (0.56) ALDH1A1SMN1; SMN2CYP2C9CYP2C19L3MBTL1
SCHEMBL7328957 0.69 KEAP1 (0.54) ALDH1A1CYP2C9CYP2C19L3MBTL1PSIP1
SCHEMBL11341852 0.69 TLR9 (0.52) TLR9ALDH1A1SMN1; SMN2CYP1A2CYP2C9
SCHEMBL1264868 0.69 PSIP1 (0.54) TLR9ALDH1A1SMN1; SMN2CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230366197-A1 Cementitious Panels with Swellable Materials and Methods of Providing a Moisture or Water Barrier in Cementitious Panels Using Swellable Materials BANK OF AMERICA, N.A., AS COLLATERAL AGENT 2023-11-16 US disclosed
US-11801662-B2 Cementitious panels with polymeric-film facing material GOLD BOND BUILDING PRODUCTS, LLC (US) 2023-10-31 US disclosed
US-11708692-B2 Cementitious panels with swellable materials and methods of providing a moisture or water barrier in cementitious panels using swellable materials GOLD BOND BUILDING PRODUCTS, LLC (US) 2023-07-25 US disclosed
EP-3105053-B1 THIN NANOCOMPOSITE FILM FOR USE IN AN ABSORBENT ARTICLE KIMBERLY CLARK CO (US) 2021-09-22 EP disclosed
US-11058791-B2 Thin nanocomposite film for use in an absorbent article KIMBERLY-CLARK WORLDWIDE, INC. (US) 2021-07-13 US disclosed
US-10869790-B2 Absorbent article package with reduced noise KIMBERLY-CLARK WORLDWIDE, INC. (US) 2020-12-22 US disclosed
US-10849800-B2 Film with reduced noise for use in an absorbent article KIMBERLY-CLARK WORLDWIDE, INC. (US) 2020-12-01 US disclosed
US-20200208398-A1 Cementitious Panels with Swellable Materials and Methods of Providing a Moisture or Water Barrier in Cementitious Panels Using Swellable Materials BANK OF AMERICA, N.A., AS COLLATERAL AGENT 2020-07-02 US disclosed
US-20200207060-A1 Cementitious Panels with Polymeric-Film Facing Material BANK OF AMERICA, N.A., AS COLLATERAL AGENT 2020-07-02 US disclosed
EP-3099733-B1 NANOCOMPOSITE PACKAGING FILM KIMBERLY CLARK CO (US) 2020-05-06 EP disclosed
US-6462122-B1 NANOCOMPOSITE CONCENTRATE OF A LAYERED SILICATE DISPERSED UNIFORMLY IN MATRIX POLYMER; INCREASED TENSILE STRENGTH; REDUCED HEAT DEGRADATION OF POLYMER; MOLDING MATERIALS; EXTRUDED FILMS AND LAMINATES; FOOD PACKAGING AMCOL INTERNATIONAL CORPORATION 2002-10-08 US disclosed
US-6407155-B1 LAYERED SILICATE DISPERSED UNIFORMILY THROUGH MATRIX; DUCTILITY, TENSILE STRENGTH, FLEXIBILITY AMCOL INTERNATIONAL CORPORATION 2002-06-18 US disclosed
US-6399690-B2 MATRIX POLYMER; SWELLABLE LAYERS; OXIDATION RESISTANCE AMCOL INTERNATIONAL CORPORATION 2002-06-04 US disclosed
US-20010033924-A1 Intercalates formed with polypropylene/maleic anhydride-modified polypropylene intercalants JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2001-10-25 US disclosed
US-20010025076-A1 Layered compositions with multi-charged onium ions as exchange cations, and their application to prepare monomer, oligomer, and polymer intercalates and nanocomposites prepared with the layered compositions of the intercalates AMCOL INTERNATIONAL CORPORATION 2001-09-27 US disclosed
US-6262162-B1 CAN BE USED AS ORGANOCLAYS FOR SORPTION OF ORGANIC MATERIALS, OR CAN BE DISPERSED UNIFORMLY INTO SOLVENTS TO INCREASE VISCOSITY OF ORGANIC LIQUIDS AMCOL INTERNATIONAL CORPORATION 2001-07-17 US disclosed
US-6232388-B1 CONTROLLING CONCENTRATION AMCOL INTERNATIONAL CORPORATION 2001-05-15 US disclosed
US-6225394-B1 USEFUL FOR BARRIER LAYERS IN MULTI-PACKAGING AND FOR COATINGS AMCOL INTERNATIONAL CORPORATION 2001-05-01 US disclosed
EP-1038834-A1 Surface modified layered silicate material and compositions containing the same AMCOL INTERNATIONAL CORPORATION (US) 2000-09-27 EP disclosed
WO-2000009605-A1 INTERCALATES FORMED WITH MXD6 NYLON INTERCALANTS AMCOL INTERNATIONAL CORPORATION (US) 2000-02-24 WO disclosed