Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 5/20 | 0.45 |
| ▸ | GSK3B | P49841 | 5/20 | 0.43 |
| ▸ | VCP | P55072 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 7/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13288684 | 0.95 | CDK2 (0.44) | CDK2GSK3BVCPNPC1RAB9A | |
| SCHEMBL13288713 | 0.91 | NPC1 (0.43) | CDK2GSK3BNPC1RAB9A | |
| SCHEMBL13289143 | 0.90 | CDK2 (0.54) | CDK2GSK3BVCPNPC1RAB9A | |
| SCHEMBL13120206 | 0.89 | CDK2 (0.58) | CDK2GSK3BVCP | |
| SCHEMBL13288867 | 0.88 | CDK2 (0.47) | CDK2GSK3BVCPABL1 | |
| SCHEMBL14545262 | 0.86 | CDK2 (0.45) | CDK2GSK3BABL1 | |
| SCHEMBL13120240 | 0.85 | CDK2 (0.56) | CDK2GSK3BNPC1RAB9A | |
| SCHEMBL13288740 | 0.85 | GSK3B (0.46) | CDK2GSK3BABL1 | |
| SCHEMBL14545893 | 0.85 | CDK2 (0.46) | CDK2GSK3B | |
| SCHEMBL13120004 | 0.84 | CDK2 (0.57) | CDK2GSK3BVCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2194058-A1 | Pyrazolopyrimidines suitable for the treatment of cancer diseases | SCHERING CORPORATION (US) | 2010-06-09 | — | — | EP | disclosed |