Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15867098 | 0.86 | NQO1 (0.36) | RAB9ALMNAL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL13290647 | 0.84 | RAB9A (0.43) | RAB9APOLBLMNAL3MBTL1ATM | |
| SCHEMBL13290649 | 0.78 | RAB9A (0.39) | RAB9APOLBLMNAL3MBTL1ATM | |
| SCHEMBL14094710 | 0.77 | RAB9A (0.38) | RAB9APOLBLMNAL3MBTL1ATM | |
| SCHEMBL13290653 | 0.77 | MEN1 (0.41) | RAB9APOLBLMNAL3MBTL1ATM | |
| SCHEMBL27864101 | 0.76 | LTA4H (0.39) | RAB9AL3MBTL1ALDH1A1NPC1MAPT | |
| SCHEMBL13290650 | 0.76 | CA1 (0.41) | RAB9APOLBLMNAL3MBTL1ATM | |
| SCHEMBL13290642 | 0.76 | SMN1; SMN2 (0.43) | RAB9APOLBLMNAL3MBTL1ATM | |
| SCHEMBL16048013 | 0.76 | RAB9A (0.48) | RAB9APOLBLMNAL3MBTL1ATM | |
| SCHEMBL13290644 | 0.75 | RAB9A (0.42) | RAB9APOLBLMNAL3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741289-B2 | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof | SCHERING CORPORATION (US) | 2010-06-22 | — | — | US | disclosed |
| US-20080207585-A1 | Substituted Azetidinone Compounds, Processes for Preparing the Same, Formulations and Uses Thereof | SCHERING CORPORATION (US) | 2008-08-28 | — | — | US | disclosed |
| US-7368563-B2 | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof | SCHERING CORPORATION (US) | 2008-05-06 | — | — | US | disclosed |
| US-20070155675-A1 | Substituted azetidinone compunds, processes for preparing the same, formulations and uses thereof | SCHERING CORPORATION (US) | 2007-07-05 | — | — | US | disclosed |
| US-7235543-B2 | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof | SCHERING CORPORATION (US) | 2007-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207585-A1 | Substituted Azetidinone Compounds, Processes for Preparing the Same, Formulations and Uses Thereof | CYP46A1, NPC1L1, PCSK9 | RAB9A 2086/4885POLB 4689/4885LMNA 818/4885 |
| US-20070155675-A1 | Substituted azetidinone compunds, processes for preparing the same, formulations and uses thereof | APOB, NPC1L1, CYP46A1 | RAB9A 3802/4885POLB 3934/4885LMNA 1989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.