Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.57 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.57 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.57 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.57 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.53 |
| ▸ | GPBAR1 | Q8TDU6 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | NT5E | P21589 | 2/20 | 0.48 |
| ▸ | TOP2A | P11388 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | F3 | P13726 | 1/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13293155 | 0.91 | SLC10A1 (0.65) | EGLN2EGLN1EGLN3P4HTMSLC10A1 | |
| SCHEMBL15457042 | 0.88 | GPBAR1 (0.57) | EGLN2EGLN1EGLN3P4HTMSLC10A1 | |
| SCHEMBL13164848 | 0.87 | TOP2A (0.59) | EGLN2EGLN1EGLN3P4HTMSLC10A1 | |
| SCHEMBL13293154 | 0.86 | LMNA (0.65) | EGLN2EGLN1EGLN3P4HTMSLC10A1 | |
| SCHEMBL13293126 | 0.86 | LMNA (0.58) | EGLN2EGLN1EGLN3P4HTMSLC10A1 | |
| SCHEMBL13293178 | 0.85 | GPBAR1 (0.69) | EGLN2EGLN1EGLN3P4HTMGPBAR1 | |
| SCHEMBL3507541 | 0.85 | GPBAR1 (0.69) | EGLN2EGLN1EGLN3P4HTMGPBAR1 | |
| SCHEMBL16704981 | 0.85 | GPBAR1 (0.69) | EGLN2EGLN1EGLN3P4HTMGPBAR1 | |
| SCHEMBL16704671 | 0.85 | EGLN2 (0.65) | EGLN2EGLN1EGLN3P4HTMGPBAR1 | |
| SCHEMBL13293160 | 0.83 | EGLN2 (0.54) | EGLN2EGLN1EGLN3P4HTMSLC10A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144688-A1 | 23-Substituted Derivatives of Lupane-type Pentacyclic Triterpenoids | ADVANCED LIFE SCIENCES, INC. (US) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144688-A1 | 23-Substituted Derivatives of Lupane-type Pentacyclic Triterpenoids | BRCA1, PGF, LSS | EGLN2 1377/4885EGLN1 717/4885EGLN3 907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.