Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | PRKACA | P17612 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28135252 | 0.89 | ADORA2A (0.52) | AURKAHSP90AA1PRKACAADORA2AMEN1 | |
| SCHEMBL28131710 | 0.88 | TNK2 (0.49) | CCNT1CDK9PIM1MEN1KMT2A | |
| SCHEMBL13294782 | 0.85 | MKNK1 (0.56) | PIM1PRKACAMEN1KMT2AIKBKB | |
| SCHEMBL7171237 | 0.84 | POLB (0.50) | AURKAHSP90AA1PRKACAADORA2AMEN1 | |
| SCHEMBL13294778 | 0.83 | CHRNA7 (0.49) | CDK9PIM1MEN1KMT2AMKNK1 | |
| SCHEMBL13294777 | 0.81 | PIM1 (0.43) | PIM1MEN1KMT2AIKBKBMKNK1 | |
| SCHEMBL13295160 | 0.80 | GABRA1 (0.43) | HPGDSPIM1MEN1KMT2AIKBKB | |
| SCHEMBL13959343 | 0.77 | MAPK13 (0.50) | PIM1MEN1KMT2AHTR2C | |
| SCHEMBL9130502 | 0.76 | RAB9A (0.44) | AURKAHSP90AA1PRKACAADORA2AMEN1 | |
| SCHEMBL13490451 | 0.76 | MEN1 (0.55) | HPGDSCCNT1CDK9PIM1SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010064597-A1 | PIPERIDINE DERIVATIVE | 武田薬品工業株式会社 (JP) | 2010-06-10 | — | — | WO | disclosed |