Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.34 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13295995 | 0.86 | LMNA (0.40) | LMNAL3MBTL1THRBATMSLC1A3 | |
| SCHEMBL7432662 | 0.85 | EPHX2 (0.42) | EPHX2NPSR1TP53L3MBTL1THRB | |
| SCHEMBL7432656 | 0.85 | EPHX2 (0.42) | EPHX2NPSR1TP53L3MBTL1THRB | |
| SCHEMBL13295976 | 0.84 | EPHX2 (0.40) | LMNAEPHX2NPSR1L3MBTL1THRB | |
| SCHEMBL13295954 | 0.83 | EPHX2 (0.42) | EPHX2NPSR1TP53L3MBTL1EPHX1 | |
| SCHEMBL38033 | 0.81 | SMN1; SMN2 (0.39) | EPHX2NPSR1TP53L3MBTL1THRB | |
| SCHEMBL27579413 | 0.79 | NPSR1 (0.40) | EPHX2NPSR1TP53L3MBTL1THRB | |
| SCHEMBL38034 | 0.78 | EPHX1 (0.40) | EPHX2NPSR1TP53THRBEPHX1 | |
| SCHEMBL38032 | 0.78 | EPHX1 (0.40) | EPHX2NPSR1TP53THRBEPHX1 | |
| SCHEMBL13295961 | 0.78 | SMN1; SMN2 (0.36) | LMNASLC1A3SLC1A2SLC1A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732018-B2 | Durable coating compositions containing novel aspartic amine compounds | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-08 | — | — | US | disclosed |
| US-7732018-B2 | Durable coating compositions containing novel aspartic amine compounds | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-08 | — | — | US | disclosed |
| EP-1833783-B1 | DURABLE COATING COMPOSITIONS CONTAINING NOVEL ASPARTIC AMINE COMPOUNDS | DU PONT (US) | 2009-04-15 | — | — | EP | disclosed |
| US-7449242-B2 | Durable coating compositions containing novel aspartic amine compounds | E.I. DU PONT DE NEMOURS & COMPANY (US) | 2008-11-11 | — | — | US | disclosed |
| US-7449242-B2 | Durable coating compositions containing novel aspartic amine compounds | E.I. DU PONT DE NEMOURS & COMPANY (US) | 2008-11-11 | — | — | US | disclosed |
| US-7166748-B2 | Durable coating compositions containing novel aspartic amine compounds | E.I. DUPONT DE NEMOURS & CO. (US) | 2007-01-23 | — | — | US | disclosed |
| US-7166748-B2 | Durable coating compositions containing novel aspartic amine compounds | E.I. DUPONT DE NEMOURS & CO. (US) | 2007-01-23 | — | — | US | disclosed |