Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38034 | 1.00 | EPHX1 (0.40) | EPHX1CACNA1BEPHX2HDAC4HDAC1 | |
| SCHEMBL11001094 | 0.94 | CYP2D6 (0.37) | EPHX1CACNA1BHDAC1HDAC6SMN1; SMN2 | |
| SCHEMBL38058 | 0.87 | EPHX1 (0.40) | EPHX1CACNA1BEPHX2HDAC4HDAC1 | |
| SCHEMBL38057 | 0.87 | EPHX1 (0.40) | EPHX1CACNA1BEPHX2HDAC4HDAC1 | |
| SCHEMBL7432656 | 0.86 | EPHX2 (0.42) | EPHX2SMN1; SMN2NPSR1THRBTP53 | |
| SCHEMBL7432662 | 0.86 | EPHX2 (0.42) | EPHX2SMN1; SMN2NPSR1THRBTP53 | |
| SCHEMBL10825239 | 0.85 | EPHX1 (0.43) | EPHX1CACNA1BEPHX2HDAC4HDAC1 | |
| SCHEMBL19744864 | 0.85 | EPHX1 (0.43) | EPHX1CACNA1BEPHX2HDAC4HDAC1 | |
| SCHEMBL38033 | 0.79 | SMN1; SMN2 (0.39) | EPHX1EPHX2GAASMN1; SMN2CYP2D6 | |
| SCHEMBL24033741 | 0.79 | EPHX1 (0.44) | EPHX1EPHX2HDAC4HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151436-A2 | NOVEL COMPOUNDS, METHOD FOR USE THEM AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | EUROSCREEN S.A. (BE) | 2011-12-08 | — | — | WO | disclosed |