Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | NPR3 | P17342 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.32 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7432656 | 0.86 | EPHX2 (0.42) | SMN1; SMN2POLBCYP2C9CYP2C19NPR3 | |
| SCHEMBL7432662 | 0.86 | EPHX2 (0.42) | SMN1; SMN2POLBCYP2C9CYP2C19NPR3 | |
| SCHEMBL13295960 | 0.81 | LMNA (0.42) | SMN1; SMN2POLBEPHX1EPHX2NPSR1 | |
| SCHEMBL13295954 | 0.81 | EPHX2 (0.42) | SMN1; SMN2POLBEPHX1EPHX2NPSR1 | |
| SCHEMBL38032 | 0.79 | EPHX1 (0.40) | SMN1; SMN2EPHX1EPHX2NPSR1GAA | |
| SCHEMBL38034 | 0.79 | EPHX1 (0.40) | SMN1; SMN2EPHX1EPHX2NPSR1GAA | |
| SCHEMBL27579413 | 0.77 | NPSR1 (0.40) | SMN1; SMN2POLBEPHX1EPHX2NPSR1 | |
| SCHEMBL14952209 | 0.76 | NPSR1 (0.41) | SMN1; SMN2POLBCYP2C9CYP2C19EPHX1 | |
| SCHEMBL19861713 | 0.76 | TSHR (0.37) | SMN1; SMN2POLBNPSR1GAAL3MBTL1 | |
| SCHEMBL2027742 | 0.76 | THRB (0.42) | SMN1; SMN2POLBEPHX1EPHX2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151436-A2 | NOVEL COMPOUNDS, METHOD FOR USE THEM AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | EUROSCREEN S.A. (BE) | 2011-12-08 | — | — | WO | disclosed |