Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13647772 | 0.72 | ACHE (0.37) | ACHEALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL5880765 | 0.71 | ALDH1A1 (0.40) | ACHEALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL12519883 | 0.69 | LMNA (0.37) | ALDH1A1HPGDMAPTKDM4EMEN1 | |
| SCHEMBL19621118 | 0.67 | LMNA (0.50) | ALDH1A1HPGDMAPTKDM4EMEN1 | |
| SCHEMBL7235362 | 0.64 | ALDH1A1 (0.33) | ACHEALDH1A1HPGD | |
| SCHEMBL979693 | 0.64 | — | — | |
| SCHEMBL18337134 | 0.63 | — | — | |
| SCHEMBL1331203 | 0.62 | — | — | |
| SCHEMBL16870057 | 0.62 | ALDH1A1 (0.33) | ACHEALDH1A1HPGDKDM4E | |
| SCHEMBL444909 | 0.60 | KDM4E (0.31) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389216-B1 | AVERMECTINS SUBSTITUTED IN THE 4\"-POSITION HAVING PESTICIDAL PROPERTIES | MERIAL INC (US) | 2017-02-22 | — | — | EP | disclosed |
| US-7732416-B2 | For protecting plants against parasitic feeding pests; also against the infestation of pets, especially cats and dogs, by fleas, ticks and nematodes; pesticides for crop protection | MERIAL LIMITED (US) | 2010-06-08 | — | — | US | disclosed |