Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3138434 | 1.00 | CA1 (0.37) | CA1CA9KMT2ASTSCA2 | |
| SCHEMBL29019030 | 1.00 | CA1 (0.37) | CA1CA9KMT2ASTSCA2 | |
| SCHEMBL11424382 | 0.96 | CA1 (0.37) | CA1CA9KMT2ASTSMAPT | |
| SCHEMBL8141255 | 0.94 | TRIM24 (0.42) | CA1CA9KMT2ASTSALDH1A1 | |
| SCHEMBL13304668 | 0.93 | CA1 (0.38) | CA1CA9STSTSHRALDH1A1 | |
| SCHEMBL7909099 | 0.89 | CA1 (0.43) | CA1CA9KMT2ASTSMAPT | |
| SCHEMBL8755171 | 0.89 | CA1 (0.43) | CA1CA9STSTSHRALDH1A1 | |
| SCHEMBL113746 | 0.89 | CA1 (0.43) | CA1CA9STSTSHRALDH1A1 | |
| SCHEMBL8755163 | 0.89 | CA1 (0.43) | CA1CA9STSTSHRALDH1A1 | |
| SCHEMBL28730832 | 0.89 | CA1 (0.43) | CA1CA9KMT2ASTSMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10836976-B2 | Polymeric viscosity modifiers for use in lubricants | AFTON CHEMICAL CORPORATION (US) | 2020-11-17 | — | — | US | claimed |
| US-8273828-B2 | Methods for introducing reactive secondary amines pendant to polymers backbones that are useful for diazeniumdiolation | MEDTRONIC VASCULAR, INC. (US) | 2012-09-25 | — | — | US | claimed |
| JP-2010534270-A | — | — | 2010-11-04 | — | — | JP | claimed |
| CN-101821300-A | Methods for introducing reactive secondary amines pendant to polymer backbones that are useful for diazeniumdiolation | MEDTRONIC VASCULAR INC | 2010-09-01 | — | — | CN | claimed |
| EP-2185603-A2 | METHODS FOR INTRODUCTING REACTIVE SECONDARY AMINES PENDANT TO POLYMER BACKBONES THAT ARE USEFUL FOR DIAZENIUMDIOLATION | Medtronic Vascular Inc. (US) | 2010-05-19 | — | — | EP | claimed |
| EP-2104522-A2 | BLOCK BIODEGRADABLE COPOLYMERS FOR MEDICAL DEVICES | Medtronic Vascular Inc. (US) | 2009-09-30 | — | — | EP | claimed |
| US-20090222088-A1 | Secondary Amine Containing Nitric Oxide Releasing Polymer Composition | MEDTRONIC VASCULAR, INC. (US) | 2009-09-03 | — | — | US | claimed |
| US-20090028966-A1 | Methods for Introducing Reactive Secondary Amines Pendant to Polymers Backbones that are Useful for Diazeniumdiolation | MEDTRONIC VASCULAR, INC. (US) | 2009-01-29 | — | — | US | claimed |
| WO-2009014829-A2 | METHODS FOR INTRODUCING REACTIVE SECONDARY AMINES PENDANT TO POLYMER BACKBONES THAT ARE USEFUL FOR DIAZENIUMDIOLATION | MEDTRONIC VASCULAR INC. (US) | 2009-01-29 | — | — | WO | claimed |
| WO-2008070356-A2 | BLOCK BIODEGRADABLE COPOLYMERS FOR MEDICAL DEVICES | MEDTRONIC VASCULAR, INC. (US) | 2008-06-12 | — | — | WO | claimed |
| US-6998072-B2 | Containing polymerizable material and photochromic compound; ophthalmic lenses | TRANSITIONS OPTICAL, INC. (US) | 2006-02-14 | — | — | US | claimed |
| EP-1451256-B1 | ARTICLES HAVING A PHOTOCHROMIC POLYMERIC COATING | TRANSITIONS OPTICAL INC (US) | 2005-06-29 | — | — | EP | claimed |
| EP-1451256-A1 | ARTICLES HAVING A PHOTOCHROMIC POLYMERIC COATING | TRANSITIONS OPTICAL, INC. (US) | 2004-09-01 | — | — | EP | claimed |
| EP-1438368-A1 | PHOTOCHROMIC POLYMERIZABLE COMPOSITIONS | TRANSITIONS OPTICAL, INC. (US) | 2004-07-21 | — | — | EP | claimed |
| US-20030143404-A1 | Articles having a photochromic polymeric coating | TRANSITIONS OPTICAL LIMITED (IE) | 2003-07-31 | — | — | US | claimed |
| US-20030136948-A1 | Photochromic polymerizable compositions | TRANSITIONS OPTICAL LIMITED (IE) | 2003-07-24 | — | — | US | claimed |
| WO-2003037998-A1 | ARTICLES HAVING A PHOTOCHROMIC POLYMERIC COATING | TRANSITIONS OPTICAL, INC. (US) | 2003-05-08 | — | — | WO | claimed |
| WO-2003038009-A1 | PHOTOCHROMIC POLYMERIZABLE COMPOSITIONS | TRANSITIONS OPTICAL, INC. (US) | 2003-05-08 | — | — | WO | claimed |
| EP-0409093-A2 | Polyamide fibers having reduced amino end groups, light-dyed and stain resistant polyamide fibers made therefrom, and method of preparation | BASF Corporation (US) | 1991-01-23 | — | — | EP | claimed |
| US-4963275-A | POLYOLEFIN MODIFIED BY AN UNSATURATED ANHYDRIDE, THE REACTION PRODUCT OF A POLYAMINE AND ACRYLIC COMPOUND AND A LACTONE OR POLYLACTONE; OIL ADDITIVES | EXXON CHEMICAL PATENTS INC. (US) | 1990-10-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090222088-A1 | Secondary Amine Containing Nitric Oxide Releasing Polymer Composition | NOS2, NOS1, NOS3 | CA1 1327/4885CA9 1143/4885KMT2A 292/4885 |
| US-20090028966-A1 | Methods for Introducing Reactive Secondary Amines Pendant to Polymers Backbones that are Useful for Diazeniumdiolation | NOS2, NOS1, NOS3 | CA1 1713/4885CA9 778/4885KMT2A 3373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.