SCHEMBL13298973

SCHEMBL13298973

Cc1ccc2nc(-c3cc(C)c(C)c(C)c3)ccc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.53
NCK1 P16333 1/20 0.50
BACE1 P56817 1/20 0.50
ESR1 P03372 1/20 0.43
ESR2 Q92731 1/20 0.43
ALDH1A1 P00352 5/20 0.42
PDE3B Q13370 2/20 0.41
PDE3A Q14432 2/20 0.41
CYP2A6 P11509 3/20 0.41
PSMB5 P28074 1/20 0.40
KDM4E B2RXH2 4/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
NQO2 P16083 1/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
HSD17B10 Q99714 1/20 0.36
PDE2A O00408 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
RAB9A P51151 2/20 0.36
NPC1 O15118 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28176596 0.88 ESR1 (0.44) CYP1A2NCK1BACE1ESR1ESR2
SCHEMBL13989403 0.87 CYP1A2 (0.52) CYP1A2NCK1BACE1ESR1ALDH1A1
SCHEMBL4128022 0.85 CYP1A2 (0.57) CYP1A2NCK1BACE1ESR1ESR2
SCHEMBL13298971 0.84 CYP1A2 (0.52) CYP1A2NCK1BACE1ESR1ESR2
SCHEMBL10147842 0.83 CYP1A2 (0.59) CYP1A2NCK1BACE1ESR1ESR2
SCHEMBL23247265 0.82 CYP1A2 (0.68) CYP1A2NCK1BACE1ESR1ESR2
SCHEMBL20660363 0.80 BACE1 (0.53) CYP1A2NCK1BACE1ESR1ESR2
SCHEMBL14500751 0.80 NCF1 (0.53) CYP1A2ALDH1A1PDE3BPDE3ACYP2A6
SCHEMBL29692924 0.80 PSMB5 (0.57) CYP1A2NCK1BACE1ESR1ESR2
SCHEMBL8830006 0.80 PSMB5 (0.57) CYP1A2NCK1BACE1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1856226-B1 RED PHOSPHORESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICES USING THE SAME LG ELECTRONICS INC (KR) 2014-07-23 EP disclosed
US-7740957-B2 Dopant iridium complexes of 2-alkylphenylquinolines and an alkanedione; dopant of the light emitting layer; host compounds are aluminum or zinc complexes; high color purity, high brightness, and long durability; flat panel displays LG ELECTRONICS INC. (KR) 2010-06-22 US disclosed
US-7740957-B2 Dopant iridium complexes of 2-alkylphenylquinolines and an alkanedione; dopant of the light emitting layer; host compounds are aluminum or zinc complexes; high color purity, high brightness, and long durability; flat panel displays LG ELECTRONICS INC. (KR) 2010-06-22 US disclosed