Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13299540 | 0.91 | NLRP3 (0.51) | NLRP3ALDH1A1SIRT2SIRT1KDM4E | |
| SCHEMBL13299537 | 0.90 | NLRP3 (0.50) | NLRP3ALDH1A1SIRT2SIRT1KDM4E | |
| SCHEMBL15940200 | 0.90 | ALDH1A1 (0.43) | NLRP3ALDH1A1ALOX15TSHRSIRT2 | |
| SCHEMBL13299528 | 0.87 | NLRP3 (0.52) | NLRP3ALDH1A1SIRT2SIRT1KDM4E | |
| SCHEMBL2456142 | 0.86 | ESR1 (0.51) | ALDH1A1ALOX15TSHRKDM4ETP53 | |
| SCHEMBL20458041 | 0.85 | ALDH1A1 (0.44) | NLRP3ALDH1A1ALOX15TSHRKDM4E | |
| SCHEMBL13299530 | 0.83 | NLRP3 (0.57) | NLRP3ALDH1A1SIRT2SIRT1KDM4E | |
| SCHEMBL26027693 | 0.83 | NLRP3 (0.36) | NLRP3ALDH1A1ALOX15TSHRPDE10A | |
| SCHEMBL15939833 | 0.83 | ALDH1A1 (0.44) | ALDH1A1ALOX15TSHRKDM4ETP53 | |
| SCHEMBL13299599 | 0.82 | NLRP3 (0.56) | NLRP3ALDH1A1SIRT2SIRT1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367223-B2 | Heteroleptic phosphorescent emitters | UNIVERSAL DISPLAY CORPORATION (US) | 2013-02-05 | — | — | US | disclosed |
| US-20100141127-A1 | PHOSPHORESCENT EMITTERS | UNIVERSAL DISPLAY CORPORATION (US) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100141127-A1 | PHOSPHORESCENT EMITTERS | PAICS, TYMP, NUDT1 | NLRP3 651/4885ALDH1A1 695/4885ALOX15 4400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.