Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 15/20 | 0.45 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30820583 | 0.83 | TLR8 (0.47) | TLR8DCPSTLR7TSHR | |
| SCHEMBL30746985 | 0.74 | GPBAR1 (0.41) | TLR8ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL30543203 | 0.73 | TLR8 (0.41) | TLR8ALDH1A1TSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30543224 | 0.73 | GPBAR1 (0.40) | TLR8ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL30402892 | 0.73 | TLR8 (0.41) | TLR8ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL4753647 | 0.72 | DCPS (0.57) | TLR8DCPSTLR7ALDH1A1TSHR | |
| SCHEMBL1458588 | 0.72 | TLR8 (0.57) | TLR8DCPSTLR7TSHRATM | |
| SCHEMBL22498767 | 0.71 | TLR8 (0.58) | TLR8DCPSTLR7ALDH1A1TSHR | |
| SCHEMBL29377718 | 0.71 | TLR8 (0.58) | TLR8DCPSTLR7ALDH1A1TSHR | |
| SCHEMBL28203089 | 0.71 | TLR8 (0.58) | TLR8DCPSTLR7ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2198867-A1 | Pyrimidine-based compounds useful as GSK-3 inhibitors | Vertex Pharmaceuticals, Inc. (US) | 2010-06-23 | — | — | EP | disclosed |