Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3331856 | 0.95 | KDM4E (0.55) | KDM4EL3MBTL1ATMMAPTALDH1A1 | |
| SCHEMBL13301588 | 0.95 | KDM4E (0.55) | KDM4EL3MBTL1ATMMAPTALDH1A1 | |
| SCHEMBL15730706 | 0.95 | KDM4E (0.55) | KDM4EL3MBTL1ATMMAPTALDH1A1 | |
| SCHEMBL19485347 | 0.95 | KDM4E (0.55) | KDM4EL3MBTL1ATMMAPTALDH1A1 | |
| SCHEMBL13301594 | 0.95 | KDM4E (0.55) | KDM4EL3MBTL1ATMMAPTALDH1A1 | |
| SCHEMBL1144158 | 0.95 | KDM4E (0.50) | KDM4EL3MBTL1ATMMAPTALDH1A1 | |
| SCHEMBL12856945 | 0.95 | KDM4E (0.50) | KDM4EL3MBTL1ATMMAPTALDH1A1 | |
| SCHEMBL13301590 | 0.95 | KDM4E (0.50) | KDM4EL3MBTL1ATMMAPTALDH1A1 | |
| SCHEMBL19429316 | 0.95 | KDM4E (0.50) | KDM4EL3MBTL1ATMMAPTALDH1A1 | |
| SCHEMBL9912865 | 0.95 | L3MBTL1 (0.45) | KDM4EL3MBTL1ATMMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100145067-A1 | NOVEL CARBAZOLES DERIVATIVE AND USE THEREOF | BANDO CHEMICAL INDUSTRIES, LTD. (JP) | 2010-06-10 | — | — | US | disclosed |
| US-20100145067-A1 | NOVEL CARBAZOLES DERIVATIVE AND USE THEREOF | BANDO CHEMICAL INDUSTRIES, LTD. (JP) | 2010-06-10 | — | — | US | disclosed |
| EP-2100880-A1 | NOVEL CARBAZOLE DERIVATIVE AND USE THEREOF | Bando Chemical Industries, Ltd. (JP) | 2009-09-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100145067-A1 | NOVEL CARBAZOLES DERIVATIVE AND USE THEREOF | GDI2, SGK2, GDI1 | KDM4E 1016/4885L3MBTL1 3298/4885ATM 1735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.