SCHEMBL13301598

SCHEMBL13301598

c1ccc(N(c2ccc(-c3ccc4c(c3)c3ccccc3n4-c3ccccc3)cc2)c2ccc(N(c3ccccc3)c3ccc(-c4ccc5c(c4)c4ccccc4n5-c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 3/20 0.55
▸ KDM4E B2RXH2 2/20 0.55
▸ ATM Q13315 1/20 0.55
▸ TSPO P30536 4/20 0.44
▸ PTGER4 P35408 1/20 0.39
▸ HDAC4 P56524 1/20 0.39
▸ KMT2A Q03164 2/20 0.36
▸ MAPK8 P45983 1/20 0.36
▸ IL1R1 P14778 1/20 0.36
▸ ALDH1A1 P00352 2/20 0.35
▸ MAPT P10636 2/20 0.35
▸ HTT P42858 2/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ HSD17B10 Q99714 1/20 0.35
▸ CYP1A2 P05177 1/20 0.34
▸ CYP3A4 P08684 1/20 0.34
▸ CYP2D6 P10635 1/20 0.34
▸ CYP2C9 P11712 1/20 0.34
▸ CYP2C19 P33261 1/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19738243 1.00 L3MBTL1 (0.55) L3MBTL1KDM4EATMTSPOPTGER4
SCHEMBL12200627 1.00 L3MBTL1 (0.55) L3MBTL1KDM4EATMTSPOPTGER4
SCHEMBL13125942 1.00 L3MBTL1 (0.55) L3MBTL1KDM4EATMTSPOPTGER4
SCHEMBL16158350 1.00 L3MBTL1 (0.55) L3MBTL1KDM4EATMTSPOPTGER4
SCHEMBL15306379 1.00 L3MBTL1 (0.55) L3MBTL1KDM4EATMTSPOPTGER4
SCHEMBL13125929 1.00 L3MBTL1 (0.55) L3MBTL1KDM4EATMTSPOPTGER4
SCHEMBL10331725 1.00 L3MBTL1 (0.55) L3MBTL1KDM4EATMTSPOPTGER4
SCHEMBL20599101 1.00 L3MBTL1 (0.55) L3MBTL1KDM4EATMTSPOPTGER4
SCHEMBL20707572 1.00 L3MBTL1 (0.55) L3MBTL1KDM4EATMTSPOPTGER4
SCHEMBL13125922 1.00 L3MBTL1 (0.55) L3MBTL1KDM4EATMTSPOPTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100145067-A1 NOVEL CARBAZOLES DERIVATIVE AND USE THEREOF BANDO CHEMICAL INDUSTRIES, LTD. (JP) 2010-06-10 — — US disclosed
US-20100145067-A1 NOVEL CARBAZOLES DERIVATIVE AND USE THEREOF BANDO CHEMICAL INDUSTRIES, LTD. (JP) 2010-06-10 — — US disclosed
EP-2100880-A1 NOVEL CARBAZOLE DERIVATIVE AND USE THEREOF Bando Chemical Industries, Ltd. (JP) 2009-09-16 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100145067-A1 NOVEL CARBAZOLES DERIVATIVE AND USE THEREOF GDI2, SGK2, GDI1 L3MBTL1 3298/4885KDM4E 1016/4885ATM 1735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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