Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MVD | P53602 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28234432 | 0.81 | TPI1 (0.46) | MVDSMN1; SMN2ALDH1A1 | |
| SCHEMBL27566176 | 0.77 | TSHR (0.56) | MVDSMN1; SMN2ALDH1A1KDM4ETSHR | |
| SCHEMBL20175276 | 0.71 | SMN1; SMN2 (0.33) | MVDSMN1; SMN2ALDH1A1 | |
| SCHEMBL1258611 | 0.71 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1KDM4ECYP1A2L3MBTL1 | |
| SCHEMBL13301621 | 0.70 | TPI1 (0.33) | ALDH1A1KDM4ECYP1A2GLAHPGD | |
| SCHEMBL49014 | 0.69 | — | — | |
| SCHEMBL20175277 | 0.69 | CHRNB2 (0.32) | MVDSMN1; SMN2 | |
| SCHEMBL11519577 | 0.68 | TSHR (0.43) | ALDH1A1KDM4ETSHRGAA | |
| SCHEMBL18052649 | 0.68 | TSHR (0.39) | ALDH1A1TSHRACHEGAA | |
| SCHEMBL10013985 | 0.67 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1KDM4ECYP1A2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100143960-A1 | CYANINE DERIVATIVES, FLUORESCENT CONJUGATES CONTAINING SAME AND USE THEREOF | CIS BIO INTERNATIONAL (FR) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100143960-A1 | CYANINE DERIVATIVES, FLUORESCENT CONJUGATES CONTAINING SAME AND USE THEREOF | C9, CBR3, C3AR1 | MVD 3851/4885SMN1; SMN2 4093/4885ALDH1A1 3628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.