Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 2/20 | 0.47 |
| ▸ | SLC10A1 | Q14973 | 2/20 | 0.47 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13301947 | 0.93 | GPBAR1 (0.48) | GPBAR1LMNANT5ESMN1; SMN2PTGES | |
| SCHEMBL13293216 | 0.88 | SLC10A1 (0.51) | GPBAR1LMNANT5ESMN1; SMN2PTGES | |
| SCHEMBL13301931 | 0.87 | PTGES (0.61) | GPBAR1LMNANT5ESMN1; SMN2PTGES | |
| SCHEMBL13301993 | 0.81 | SLC10A1 (0.70) | GPBAR1LMNANT5ESMN1; SMN2PTGES | |
| SCHEMBL13293140 | 0.81 | GPBAR1 (0.60) | GPBAR1LMNANT5ESMN1; SMN2PTGES | |
| SCHEMBL13301992 | 0.80 | SLC10A1 (0.64) | GPBAR1LMNANT5ESMN1; SMN2PTGES | |
| SCHEMBL13301976 | 0.80 | SLC10A1 (0.57) | GPBAR1LMNANT5ESMN1; SMN2SLC10A1 | |
| SCHEMBL13293134 | 0.80 | GPBAR1 (0.59) | GPBAR1LMNANT5ESMN1; SMN2PTGES | |
| SCHEMBL13164844 | 0.79 | PTGES (0.58) | GPBAR1LMNANT5ESMN1; SMN2PTGES | |
| SCHEMBL13293224 | 0.79 | SLC10A1 (0.60) | GPBAR1LMNANT5ESMN1; SMN2PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010068668-A1 | 23-SUBSTITUTED DERIVATIVES OF LUPANE-TYPE PENTACYCLIC TRITERPENOIDS | ADVANCED LIFE SCIENCES, INC. (US) | 2010-06-17 | — | — | WO | disclosed |