Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 4/20 | 0.36 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13969930 | 0.83 | ATM (0.52) | ATMPIM1PIM3PIM2HTR2A | |
| SCHEMBL12376 | 0.78 | ATM (0.56) | ATMHTR2AHTR1DIDO1KDM4E | |
| SCHEMBL29777537 | 0.78 | ATM (0.56) | ATMHTR2AHTR1DIDO1KDM4E | |
| Ammonia Solution, Strong SCHEMBL23704299 | 0.77 | ATM (0.54) | ATMHTR2AHTR1DIDO1KDM4E | |
| SCHEMBL12524714 | 0.75 | ATM (0.52) | ATMPIM1PIM3PIM2HTR2A | |
| SCHEMBL4086846 | 0.75 | GPR84 (0.58) | ATMHTR2AIDO1LMNANR4A2 | |
| SCHEMBL1542423 | 0.75 | GPR84 (0.58) | ATMHTR2AIDO1LMNANR4A2 | |
| SCHEMBL664847 | 0.75 | HTR2C (0.53) | ATMHTR2AHTR1DIDO1KDM4E | |
| SCHEMBL3116936 | 0.75 | ATM (0.52) | ATMHTR2AHTR1DKDRHTR1B | |
| SCHEMBL325102 | 0.75 | GPR84 (0.58) | ATMHTR2AKDM4EHTR2CGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010060214-A1 | HYBRID -IONONE AND CURCUMIN MOLECULES AS ANTICANCER AGENTS | TRT PHARMA INC . (CA) | 2010-06-03 | — | — | WO | disclosed |