Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 5/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.51 |
| ▸ | HTR2A | P28223 | 4/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.51 |
| ▸ | HTR1D | P28221 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.51 |
| ▸ | HTR2B | P41595 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HTR1B | P28222 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.51 |
| ▸ | HTR3B | O95264 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | HTR1E | P28566 | 1/20 | 0.51 |
| ▸ | HTR1F | P30939 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2550995 | 0.83 | KDM4E (0.56) | HTR2CATMHTR1ACYP2D6HTR2A | |
| SCHEMBL30686491 | 0.78 | HTR2C (0.56) | HTR2CHTR1ACYP2D6HTR2ACYP2C9 | |
| SCHEMBL29777537 | 0.78 | ATM (0.56) | HTR2CATMHTR1AHTR2AHTR1D | |
| SCHEMBL12376 | 0.78 | ATM (0.56) | HTR2CATMHTR1AHTR2AHTR1D | |
| SCHEMBL5259883 | 0.78 | HTR2C (0.56) | HTR2CHTR1ACYP2D6HTR2ACYP2C9 | |
| SCHEMBL5435851 | 0.78 | HTR2C (0.56) | HTR2CHTR1ACYP2D6HTR2ACYP2C9 | |
| Ammonia Solution, Strong SCHEMBL23704299 | 0.77 | ATM (0.54) | HTR2CATMHTR1AHTR2AHTR1D | |
| SCHEMBL21291518 | 0.77 | HTR2C (0.55) | HTR2CHTR1ACYP2D6HTR2ACYP2C9 | |
| SCHEMBL29638857 | 0.76 | SRC (0.48) | HTR2CATMCYP2D6HTR2ACYP1A2 | |
| SCHEMBL435044 | 0.76 | SRC (0.48) | HTR2CATMCYP2D6HTR2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017178511-A1 | METHOD OF TREATMENT OF PARKINSONISM | FUNDACIÓ CENTRE DE REGULACIÓ GENÒMICA (ES) | 2017-10-19 | — | — | WO | claimed |
| EP-3231434-A1 | METHOD OF TREATMENT OF PARKINSONISM | Fundacio Centre de Regulacio Genomica (ES) | 2017-10-18 | — | — | EP | claimed |
| US-8808721-B2 | Bed bug attractants and methods for trapping bed bugs | SPRINGSTAR INC. (US) | 2014-08-19 | — | — | US | claimed |
| US-20120285076-A1 | BED BUG ATTRACTANTS AND METHODS FOR TRAPPING BED BUGS | SPRINGSTAR INC. (US) | 2012-11-15 | — | — | US | claimed |
| US-7825146-B2 | Sulfonamide derivative having isoxazole ring | SHIONOGI & CO., LTD. (JP) | 2010-11-02 | — | — | US | claimed |
| EP-2185510-A2 | NEW SALTS OF BAZEDOXIFENE | Zentiva, K.S. (CZ) | 2010-05-19 | — | — | EP | claimed |
| WO-2009051910-A1 | COMPOUNDS HAVING ACTIVITY IN INCREASING ION TRANSPORT BY MUTANT-CFTR AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-04-23 | — | — | WO | claimed |
| WO-2009012734-A2 | NEW SALTS OF BAZEDOXIFENE | ZENTIVA A.S. (CZ) | 2009-01-29 | — | — | WO | claimed |
| US-20060183770-A1 | Sulfonamide derivative having isoxazole ring | SHIONOGI & CO., LTD. (JP) | 2006-08-17 | — | — | US | claimed |
| EP-1650199-A1 | SULFONAMIDE DERIVATIVE HAVING ISOXAZOLE RING | SHIONOGI & CO., LTD. (JP) | 2006-04-26 | — | — | EP | claimed |
| US-5205837-A | Formed in situ by oxidation of indole compound | L'OREAL (FR) | 1993-04-27 | — | — | US | claimed |
| WO-1993005754-A1 | FINE DISPERSION OF MELANIC PIGMENTS, ITS PREPARATION AND UTILISATION IN COSMETICS | L'OREAL (FR) | 1993-04-01 | — | — | WO | claimed |
| WO-1993002655-A1 | PROCESS FOR THE TEMPORARY DYEING OF KERATIN FIBRES INVOLVING AN INSOLUBLE PIGMENT OBTAINED BY THE OXIDATIVE POLYMERISATION OF INDOLE DERIVATIVES | L'OREAL (FR) | 1993-02-18 | — | — | WO | claimed |
| WO-1993000068-A1 | METHOD FOR PREPARING SUBMICRON PARTICLES IN THE PRESENCE OF LIPID VESICLES, AND CORRESPONDING COMPOSITIONS | L'OREAL (FR) | 1993-01-07 | — | — | WO | claimed |
| EP-0518773-A1 | Cosmetic composition containing a blend of metallic oxids nanopigments and melanic pigments | L'OREAL (FR) | 1992-12-16 | — | — | EP | claimed |
| EP-0504347-A1 | COSMETIC COMPOSITION COMPRISING A DISPERSION OF LIPIDIC VESICLES AS WELL AS MELANIC PIGMENTS. | OREAL (FR) | 1992-09-23 | — | — | EP | claimed |
| WO-1992005761-A1 | COSMETIC COMPOSITION COMPRISING A DISPERSION OF LIPIDIC VESICLES AS WELL AS MELANIC PIGMENTS | L'OREAL (FR) | 1992-04-16 | — | — | WO | claimed |
| EP-0467767-A1 | Product based on flaky particles containing melanine pigment and process for their preparation | L'OREAL (FR) | 1992-01-22 | — | — | EP | claimed |
| US-5034015-A | Fade resistant hair dyes with better coloring ability | L'OREAL (FR) | 1991-07-23 | — | — | US | claimed |
| US-4199512-A | Compounds for alleviating hypertension | E. R. SQUIBB & SONS, INC. (US) | 1980-04-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183770-A1 | Sulfonamide derivative having isoxazole ring | MMP1, ARSA, MMP3 | HTR2C 1611/4885ATM 4206/4885HTR1A 1536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.