Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | P4HB | P07237 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13304409 | 0.91 | ALDH1A1 (0.48) | ALDH1A1TSHRRAB9AHSD17B10SIGMAR1 | |
| SCHEMBL3255333 | 0.90 | ALDH1A1 (0.58) | ALDH1A1TSHRRAB9AHSD17B10SIGMAR1 | |
| SCHEMBL3252274 | 0.86 | ALDH1A1 (0.76) | ALDH1A1TSHRRAB9AHSD17B10SIGMAR1 | |
| SCHEMBL3252433 | 0.83 | ALDH1A1 (0.57) | ALDH1A1TSHRRAB9AHSD17B10SIGMAR1 | |
| SCHEMBL3253325 | 0.82 | ALDH1A1 (0.56) | ALDH1A1TSHRRAB9AHSD17B10SIGMAR1 | |
| SCHEMBL3257338 | 0.81 | ALDH1A1 (0.77) | ALDH1A1TSHRRAB9AHSD17B10SIGMAR1 | |
| SCHEMBL3255205 | 0.81 | ALDH1A1 (0.49) | ALDH1A1TSHRRAB9AHSD17B10SIGMAR1 | |
| SCHEMBL13856761 | 0.78 | ALDH1A1 (0.74) | ALDH1A1TSHRRAB9AHSD17B10SIGMAR1 | |
| SCHEMBL13304768 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TSHRRAB9AHSD17B10SIGMAR1 | |
| SCHEMBL3251466 | 0.73 | MAOA (0.51) | ALDH1A1TSHRRAB9AHSD17B10SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1890672-B1 | USE OF CHROMONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2010-06-02 | — | — | EP | disclosed |