Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.42 |
| ▸ | DCTPP1 | Q9H773 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11943268 | 0.84 | DCTPP1 (0.42) | CNR1DGAT1DCTPP1ALDH1A1RXFP1 | |
| SCHEMBL11943154 | 0.77 | GLA (0.49) | DGAT1DCTPP1ALDH1A1RXFP1SMN1; SMN2 | |
| SCHEMBL11943475 | 0.75 | ALDH1A1 (0.44) | CNR1DGAT1DCTPP1ALDH1A1RXFP1 | |
| SCHEMBL13304363 | 0.73 | MAPT (0.51) | DCTPP1ALDH1A1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL11943266 | 0.72 | NPC1 (0.51) | DCTPP1ALDH1A1RXFP1SMN1; SMN2MAPT | |
| SCHEMBL11943166 | 0.70 | NPC1 (0.51) | DGAT1DCTPP1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11943165 | 0.69 | PANK3 (0.47) | DCTPP1ALDH1A1SMN1; SMN2MAPTFAAH | |
| SCHEMBL11943160 | 0.68 | FAAH (0.56) | DCTPP1ALDH1A1RXFP1SMN1; SMN2MAPT | |
| SCHEMBL11943275 | 0.68 | FAAH (0.52) | ALDH1A1MAPTFAAHKDM4EMEN1 | |
| SCHEMBL13329125 | 0.68 | FAAH (0.48) | DCTPP1SMN1; SMN2MAPTFAAHKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100158992-A1 | PIPERAZINE-SUBSTITUTED PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS | SCHERING CORPORATION (US) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100158992-A1 | PIPERAZINE-SUBSTITUTED PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS | DPM1, GMPS, MAN2A1 | CNR1 4506/4885DGAT1 4292/4885DCTPP1 209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.