Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | PTPRB | P23467 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | PTEN | P60484 | 1/20 | 0.40 |
| ▸ | PTPMT1 | Q8WUK0 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28186660 | 0.79 | MAOA (0.57) | CAPN1FFAR1PRMT1PTPRBCDC25A | |
| SCHEMBL1617652 | 0.79 | DRD2 (0.60) | CAPN1MAPTLMNA | |
| SCHEMBL27705549 | 0.79 | CYP4F2 (0.49) | CAPN1FFAR1PRMT1PTPRBCDC25A | |
| SCHEMBL27705548 | 0.79 | CYP4F2 (0.49) | CAPN1FFAR1PRMT1PTPRBCDC25A | |
| SCHEMBL4604250 | 0.79 | MAOA (0.57) | CAPN1FFAR1PRMT1PTPRBCDC25A | |
| SCHEMBL2857831 | 0.78 | TAAR1 (0.58) | FFAR1 | |
| SCHEMBL2754670 | 0.78 | TAAR1 (0.58) | CAPN1FFAR1 | |
| SCHEMBL30344632 | 0.78 | TAAR1 (0.58) | FFAR1 | |
| SCHEMBL3053513 | 0.78 | TAAR1 (0.58) | ALDH1A1LMNA | |
| SCHEMBL22047275 | 0.78 | ALDH1A1 (0.60) | CAPN1FFAR1PRMT1PTPRBCDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537116-B1 | PYRAZOLOPYRIMIDINES SUITABLE FOR THE TREATMENT OF CANCER DISEASES | SCHERING CORP (US) | 2010-06-02 | — | — | EP | disclosed |