Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13352793 | 0.77 | EED (0.39) | ALDH1A1CES1NOTUMMEN1KMT2A | |
| SCHEMBL19122704 | 0.76 | CES1 (0.53) | ALDH1A1CES1NOTUMMEN1KMT2A | |
| SCHEMBL20088341 | 0.76 | CES1 (0.44) | ALDH1A1CES1NOTUMMEN1KMT2A | |
| SCHEMBL11880068 | 0.75 | ROCK1 (0.50) | ALDH1A1CES1NOTUMMEN1KMT2A | |
| SCHEMBL15325413 | 0.75 | P2RY1 (0.37) | ALDH1A1MAP2K1NOTUMMEN1KMT2A | |
| SCHEMBL12721274 | 0.74 | HTT (0.43) | ALDH1A1GAAMAP2K1CES1NOTUM | |
| SCHEMBL14933470 | 0.74 | NPC1 (0.36) | MAP2K1MEN1KMT2AUSP2SMN1; SMN2 | |
| SCHEMBL13152974 | 0.73 | L3MBTL1 (0.39) | ALDH1A1CES1NOTUMMEN1KMT2A | |
| SCHEMBL15325421 | 0.73 | MAP2K1 (0.51) | ALDH1A1MAP2K1NOTUMMEN1KMT2A | |
| SCHEMBL1585025 | 0.72 | CES1 (0.47) | ALDH1A1GAAMAP2K1CES1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8759394-B2 | 4-hydroxybutyric acid analogs | CONCERT PHARMACEUTICALS, INC. (US) | 2014-06-24 | — | — | US | disclosed |
| US-20100157202-A1 | CONJUGATED POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100157202-A1 | CONJUGATED POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME | SLC30A6, SLC43A1, SLC39A3 | ALDH1A1 2399/4885GAA 3766/4885MAP2K1 4430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.