Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16389453 | 0.80 | HSD17B3 (0.36) | NPC1RAB9ALMNASMN1; SMN2KMT2A | |
| SCHEMBL18326501 | 0.77 | NPC1 (0.40) | NPC1RAB9ALMNASMN1; SMN2PKM | |
| SCHEMBL16389432 | 0.77 | KDM1A (0.33) | NPC1RAB9ALMNASMN1; SMN2PKM | |
| SCHEMBL16389446 | 0.77 | HTR2A (0.32) | NPC1RAB9ALMNASMN1; SMN2PKM | |
| SCHEMBL16389447 | 0.74 | RAB9A (0.46) | NPC1RAB9ALMNASMN1; SMN2PKM | |
| SCHEMBL13308993 | 0.74 | ALDH1A1 (0.43) | SMN1; SMN2KMT2AMAP2K1MEN1USP2 | |
| SCHEMBL16389371 | 0.74 | PDE6D (0.37) | NPC1RAB9ALMNASMN1; SMN2PKM | |
| SCHEMBL14933439 | 0.73 | TYRO3 (0.36) | NPC1RAB9ALMNASMN1; SMN2MAPT | |
| SCHEMBL20152308 | 0.72 | HTT (0.38) | NPC1RAB9ALMNASMN1; SMN2MAPT | |
| SCHEMBL22198458 | 0.71 | LMNA (0.41) | NPC1RAB9ALMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9337430-B2 | Organic electroluminescent device | MERCK PATENT GMBH (DE) | 2016-05-10 | — | — | US | disclosed |
| US-9337430-B2 | Organic electroluminescent device | MERCK PATENT GMBH (DE) | 2016-05-10 | — | — | US | disclosed |
| EP-2773721-B1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2015-11-25 | — | — | EP | disclosed |
| US-20140249308-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2014-09-04 | — | — | US | disclosed |
| US-20140249308-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2014-09-04 | — | — | US | disclosed |
| WO-2013064206-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2013-05-10 | — | — | WO | disclosed |