Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | CACNA1C | Q13936 | 5/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 4/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 4/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 4/20 | 1.00 |
| ▸ | TSHR | P16473 | 3/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 3/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.62 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.62 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.62 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718828 | 1.00 | CYP1A2 (1.00) | CYP1A2ADORA3MAPTCACNA1CCYP3A4 | |
| SCHEMBL2845539 | 1.00 | CYP1A2 (1.00) | CYP1A2ADORA3MAPTCACNA1CCYP3A4 | |
| SCHEMBL30897545 | 1.00 | CYP1A2 (1.00) | CYP1A2ADORA3MAPTCACNA1CCYP3A4 | |
| SCHEMBL29359402 | 1.00 | CYP1A2 (1.00) | CYP1A2ADORA3MAPTCACNA1CCYP3A4 | |
| SCHEMBL14612812 | 0.90 | CYP1A2 (0.82) | CYP1A2ADORA3MAPTCACNA1CCYP3A4 | |
| SCHEMBL7265346 | 0.89 | CYP1A2 (0.80) | CYP1A2ADORA3MAPTCACNA1CCYP3A4 | |
| SCHEMBL11369967 | 0.89 | CYP1A2 (0.79) | CYP1A2ADORA3MAPTCACNA1CCYP3A4 | |
| SCHEMBL11004406 | 0.89 | CYP1A2 (0.79) | CYP1A2ADORA3MAPTCACNA1CCYP3A4 | |
| SCHEMBL7272013 | 0.88 | MAPT (0.79) | CYP1A2ADORA3MAPTCACNA1CCYP3A4 | |
| SCHEMBL28830138 | 0.87 | MAPT (0.78) | CYP1A2ADORA3MAPTCACNA1CCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170065568-A1 | METHODS AND COMPOUNDS FOR CALCIUM ION CHANNEL REGULATION | DUKE UNIVERSITY | 2017-03-09 | — | — | US | claimed |
| US-9539222-B2 | Methods to inhibit intracellular growth of bacteria and to treat bacteria-mediated diseases | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2017-01-10 | — | — | US | claimed |
| US-20150209308-A1 | METHODS TO INHIBIT INTRACELLULAR GROWTH OF BACTERIA AND TO TREAT BACTERIA-MEDIATED DISEASES | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH | 2015-07-30 | — | — | US | claimed |
| US-20140274905-A1 | METHODS AND COMPOUNDS FOR CALCIUM ION CHANNEL REGULATION | DUKE UNIVERSITY (US) | 2014-09-18 | — | — | US | claimed |
| WO-2014039011-A1 | METHODS TO INHIBIT INTRACELLULAR GROWTH OF BACTERIA AND TO TREAT BACTERIA-MEDIATED DISEASES | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-03-13 | — | — | WO | claimed |
| US-20100130476-A1 | COMPOUNDS THAT INDUCE PANCREATIC BETA-CELL EXPANSION | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-05-27 | — | — | US | claimed |
| US-4764516-A | Mixtures of optically active nitrodihydropyridines active on the circulatory system | BAYER AKTIENGESELLSCHAFT (DE) | 1988-08-16 | — | — | US | claimed |
| US-12263143-B2 | Ionic channel modulation as a method for treating tumors through inflammasome activation | INSTITUT PASTEUR DE MONTEVIDEO (UY) | 2025-04-01 | — | — | US | disclosed |
| US-12194031-B2 | Compounds for use in regulating follicle maturation | AARHUS UNIVERSITET (DK) | 2025-01-14 | — | — | US | disclosed |
| EP-4129285-B1 | COMPOUNDS FOR USE IN REGULATING FOLLICLE MATURATION | UNIV AARHUS (DK) | 2024-11-20 | — | — | EP | disclosed |
| EP-4423254-A1 | COMPOSITIONS AND METHODS FOR PROMOTING IN VITRO MATURATION OF CELLS | Memorial Sloan Kettering Cancer Center (US) | 2024-09-04 | — | — | EP | disclosed |
| US-20240279600-A1 | COMPOSITIONS AND METHODS FOR PROMOTING IN VITRO MATURATION OF CELLS | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2024-08-22 | — | — | US | disclosed |
| WO-2023076554-A9 | COMPOSITIONS AND METHODS FOR PROMOTING IN VITRO MATURATION OF CELLS | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2024-07-11 | — | — | WO | disclosed |
| US-4920225-A | Resolution of 1,4-dihydropyridine derivatives | LABORATOIRES SYNTEX S.A. (FR) | 1990-04-24 | — | — | US | disclosed |
| US-4895855-A | VASOCILATION | BAYER AKTIENGESELLSCHAFT (DE) | 1990-01-23 | — | — | US | disclosed |
| US-4764516-A | Mixtures of optically active nitrodihydropyridines active on the circulatory system | BAYER AKTIENGESELLSCHAFT (DE) | 1988-08-16 | — | — | US | disclosed |
| EP-0273349-A2 | Resolution of 1,4-dihydropyridine derivatives | LABORATOIRES SYNTEX S.A. (FR) | 1988-07-06 | — | — | EP | disclosed |
| EP-0240257-A2 | Compounds and pharmaceutical preparations having calcium - regulatory activity | University of Lancaster (GB) | 1987-10-07 | — | — | EP | disclosed |
| US-4532248-A | Administering 1,4-dihydropyridine derivative exhibiting positive inotropic activity | BAYER AKTIENGESELLSCHAFT (DE) | 1985-07-30 | — | — | US | disclosed |
| US-4248873-A | Nitro-substituted 1,4-dihydropyridines, processes for _their production and their medicinal use | BAYER AKTIENGESELLSCHAFT (DE) | 1981-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130476-A1 | COMPOUNDS THAT INDUCE PANCREATIC BETA-CELL EXPANSION | IAPP, PNLIP, GPR119 | CYP1A2 4857/4885ADORA3 2848/4885MAPT 2817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.