Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA4 | P22748 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13997485 | 0.92 | MEN1 (0.45) | MEN1KMT2AKDM4EPOLBTDP1 | |
| SCHEMBL15492671 | 0.88 | MEN1 (0.47) | MEN1KMT2AKDM4ECA12CA1 | |
| SCHEMBL17276977 | 0.86 | TSHR (0.44) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL13253969 | 0.86 | MEN1 (0.45) | MEN1KMT2AKDM4EPOLBTDP1 | |
| SCHEMBL23729801 | 0.85 | MEN1 (0.47) | MEN1KMT2AKDM4EPOLBTDP1 | |
| SCHEMBL22856481 | 0.85 | MEN1 (0.47) | MEN1KMT2AKDM4EPOLBTDP1 | |
| SCHEMBL19658251 | 0.84 | MEN1 (0.44) | MEN1KMT2AKDM4ECA12CA1 | |
| SCHEMBL24002485 | 0.84 | KDM4E (0.44) | MEN1KMT2AKDM4EPOLBTDP1 | |
| SCHEMBL20149247 | 0.84 | MEN1 (0.44) | MEN1KMT2AKDM4ECA12CA1 | |
| SCHEMBL25129049 | 0.84 | KDM4E (0.44) | MEN1KMT2AKDM4EPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11649326-B2 | Functional, segregated, charged telodendrimers and nanocarriers and methods of making and using same | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2023-05-16 | — | — | US | disclosed |
| US-11369688-B2 | Hybrid telodendrimers | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-06-28 | — | — | US | disclosed |
| US-11192978-B2 | Reversibly crosslinked micelle systems | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-12-07 | — | — | US | disclosed |
| US-10967003-B2 | Functional segregated telodendrimers and nanocarriers and methods of making and using same | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2021-04-06 | — | — | US | disclosed |
| US-20200254012-A1 | FUNCTIONAL SEGREGATED TELODENDRIMERS AND NANOCARRIERS AND METHODS OF MAKING AND USING SAME | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2020-08-13 | — | — | US | disclosed |
| US-10463694-B2 | Functional segregated telodendrimers and nanocarriers and methods of making and using same | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2019-11-05 | — | — | US | disclosed |
| US-20190112423-A1 | REVERSIBLY CROSSLINKED MICELLE SYSTEMS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-04-18 | — | — | US | disclosed |
| US-20180036417-A1 | PORPHYRIN MODIFIED TELODENDRIMERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-02-08 | — | — | US | disclosed |
| US-20170252456-A1 | FUNCTIONAL SEGREGATED TELODENDRIMERS AND NANOCARRIERS AND METHODS OF MAKING AND USING SAME | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2017-09-07 | — | — | US | disclosed |
| US-20160244494-A1 | STABILIZED POLYPEPTIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-08-25 | — | — | US | disclosed |
| US-20100136034-A1 | NOVEL MULTIMERIC MOLECULES, A PROCESS FOR PREPARING THE SAME AND THE USE THEREOF FOR MANUFACTURING MEDICINAL DRUGS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200254012-A1 | FUNCTIONAL SEGREGATED TELODENDRIMERS AND NANOCARRIERS AND METHODS OF MAKING AND USING SAME | TTI2, TELO2, BICRA | MEN1 3336/4885KMT2A 3472/4885KDM4E 3226/4885 |
| US-11369688-B2 | Hybrid telodendrimers | TELO2, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HTT | MEN1 3409/4885KMT2A 3818/4885KDM4E 4571/4885 |
| US-20180036417-A1 | PORPHYRIN MODIFIED TELODENDRIMERS | CETP, NR1H4, ABCB4 | MEN1 2375/4885KMT2A 3192/4885KDM4E 3088/4885 |
| US-20100136034-A1 | NOVEL MULTIMERIC MOLECULES, A PROCESS FOR PREPARING THE SAME AND THE USE THEREOF FOR MANUFACTURING MEDICINAL DRUGS | TNFRSF1A, TNFRSF9, CD40 | MEN1 2811/4885KMT2A 4303/4885KDM4E 2889/4885 |
| US-11192978-B2 | Reversibly crosslinked micelle systems | CETP, NR1H4, ABCB4 | MEN1 2041/4885KMT2A 3079/4885KDM4E 2907/4885 |
| US-20190112423-A1 | REVERSIBLY CROSSLINKED MICELLE SYSTEMS | CETP, NR1H4, ABCB4 | MEN1 2041/4885KMT2A 3079/4885KDM4E 2907/4885 |
| US-10967003-B2 | Functional segregated telodendrimers and nanocarriers and methods of making and using same | TTI2, TELO2, BICRA | MEN1 3336/4885KMT2A 3472/4885KDM4E 3226/4885 |
| US-20160244494-A1 | STABILIZED POLYPEPTIDES AND USES THEREOF | JAK2, STAT5A, STAT3 | MEN1 1617/4885KMT2A 4018/4885KDM4E 4472/4885 |
| US-10463694-B2 | Functional segregated telodendrimers and nanocarriers and methods of making and using same | TTI2, TELO2, BICRA | MEN1 3336/4885KMT2A 3472/4885KDM4E 3226/4885 |
| US-11649326-B2 | Functional, segregated, charged telodendrimers and nanocarriers and methods of making and using same | TSPO, TBCA, TTI2 | MEN1 2082/4885KMT2A 2392/4885KDM4E 2282/4885 |
| US-20170252456-A1 | FUNCTIONAL SEGREGATED TELODENDRIMERS AND NANOCARRIERS AND METHODS OF MAKING AND USING SAME | TTI2, TELO2, BICRA | MEN1 3336/4885KMT2A 3472/4885KDM4E 3226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.