Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 2/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 3/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CASP9 | P55211 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3906100 | 0.78 | CCNB2 (0.49) | GSK3BCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL8765618 | 0.78 | SRD5A1 (0.41) | AHRTDP2CASP3CASP7CASP9 | |
| SCHEMBL837443 | 0.77 | AHR (0.61) | GSK3BCDK5CCNB2CDK1CCNB1 | |
| SCHEMBL13312445 | 0.76 | BRD4 (0.44) | GSK3BCDK5PIM1CSNK1A1DYRK1A | |
| SCHEMBL30049302 | 0.75 | TDP2 (0.37) | AHRTDP2CASP3CASP7CASP9 | |
| SCHEMBL10710535 | 0.74 | AHR (0.53) | GSK3BCDK5CCNB2CDK1CCNB1 | |
| SCHEMBL29783221 | 0.71 | GSK3B (0.35) | GSK3BCDK5CCNB2CDK1CCNB1 | |
| SCHEMBL935810 | 0.71 | CES1 (0.60) | CDK5PIM1CSNK1A1ROCK1DYRK1A | |
| SCHEMBL29440762 | 0.71 | CES1 (0.60) | CDK5PIM1CSNK1A1ROCK1DYRK1A | |
| SCHEMBL3715989 | 0.70 | MAPT (0.64) | CDK5PIM1CSNK1A1ROCK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160314-A1 | Small Molecule Inhibitors of Toll-Like Receptor 9 | LIPFORD GRAYSON B | 2010-06-24 | — | — | US | disclosed |
| US-20100160314-A1 | Small Molecule Inhibitors of Toll-Like Receptor 9 | LIPFORD GRAYSON B | 2010-06-24 | — | — | US | disclosed |
| WO-2008030455-A2 | SMALL MOLECULE INHIBITORS OF TOLL-LIKE RECEPTOR 9 | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2008-03-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160314-A1 | Small Molecule Inhibitors of Toll-Like Receptor 9 | TLR9, TLR3, TLR1 | GSK3B 332/4885CDK5 2972/4885CCNB2 4372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.