Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SPNS2 | Q8IVW8 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13315805 | 0.87 | CA12 (0.47) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL13315792 | 0.87 | CA12 (0.47) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL13315798 | 0.85 | CA12 (0.45) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL13315784 | 0.83 | KDM4E (0.47) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL3550958 | 0.83 | SRC (0.52) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL13315786 | 0.78 | P2RY14 (0.47) | CA12CA9SRCAPP | |
| SCHEMBL1819968 | 0.76 | MAOB (0.60) | NPC1RAB9AL3MBTL1MAOAMAOB | |
| SCHEMBL13315799 | 0.73 | MAPT (0.58) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL3550061 | 0.73 | MAPT (0.60) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL12527306 | 0.72 | MAPT (0.45) | MEN1KMT2ANPC1RAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745229-B2 | Chemoselective fluorgenic molecular linkers and methods for their preparation and use | UNIVERSITY OF SOUTH CAROLINA | 2010-06-29 | — | — | US | disclosed |
| US-20070224695-A1 | Chemoselective Fluorgenic Molecular Linkers and Methods for Their Preparation and Use | UNIVERSITY OF SOUTH CAROLINA (US) | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070224695-A1 | Chemoselective Fluorgenic Molecular Linkers and Methods for Their Preparation and Use | KIT, HLCS, ALK | MEN1 418/4885KMT2A 1042/4885CA12 283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.