Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 13/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3550958 | 0.87 | SRC (0.52) | PTGS2ABCG2CA12CA9SRC | |
| SCHEMBL13315784 | 0.85 | KDM4E (0.47) | PTGS2CA12CA9SRCAPP | |
| SCHEMBL13315795 | 0.83 | ABCG2 (0.52) | PTGS2ABCG2CA12CA9 | |
| SCHEMBL13315783 | 0.78 | MEN1 (0.49) | CA12CA9SRCAPP | |
| SCHEMBL13315785 | 0.76 | RAB9A (0.44) | CA12CA9SRCAPP | |
| SCHEMBL13315790 | 0.75 | MIF (0.54) | ABCG2SRC | |
| SCHEMBL2248079 | 0.75 | BCHE (0.44) | PTGS2ABCG2CA12CA9SRC | |
| SCHEMBL13315799 | 0.73 | MAPT (0.58) | — | |
| SCHEMBL3550061 | 0.72 | MAPT (0.60) | — | |
| SCHEMBL18031113 | 0.72 | ABCG2 (0.54) | P2RY14PTGS2ABCG2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745229-B2 | Chemoselective fluorgenic molecular linkers and methods for their preparation and use | UNIVERSITY OF SOUTH CAROLINA | 2010-06-29 | — | — | US | disclosed |
| US-7745229-B2 | Chemoselective fluorgenic molecular linkers and methods for their preparation and use | UNIVERSITY OF SOUTH CAROLINA | 2010-06-29 | — | — | US | disclosed |
| US-20070224695-A1 | Chemoselective Fluorgenic Molecular Linkers and Methods for Their Preparation and Use | UNIVERSITY OF SOUTH CAROLINA (US) | 2007-09-27 | — | — | US | disclosed |
| US-20070224695-A1 | Chemoselective Fluorgenic Molecular Linkers and Methods for Their Preparation and Use | UNIVERSITY OF SOUTH CAROLINA (US) | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070224695-A1 | Chemoselective Fluorgenic Molecular Linkers and Methods for Their Preparation and Use | KIT, HLCS, ALK | P2RY14 1659/4885PTGS2 4608/4885ABCG2 383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.