Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 5/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.44 |
| ▸ | ESRRB | O95718 | 1/20 | 0.43 |
| ▸ | ESRRA | P11474 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | AKR1A1 | P14550 | 2/20 | 0.42 |
| ▸ | CBR1 | P16152 | 2/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13315783 | 0.87 | MEN1 (0.49) | CA12CA1CA2CA9S1PR1 | |
| SCHEMBL13315798 | 0.86 | CA12 (0.45) | CA12CA1CA2CA9S1PR1 | |
| SCHEMBL13315789 | 0.84 | MIF (0.56) | S1PR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL13315805 | 0.83 | CA12 (0.47) | CA12CA1CA2CA9S1PR1 | |
| SCHEMBL13315790 | 0.82 | MIF (0.54) | NPC1ATMABCB1 | |
| SCHEMBL18523587 | 0.77 | ESR2 (0.67) | AKR1B10AKR1B1MEN1KMT2AAKR1A1 | |
| SCHEMBL25853393 | 0.76 | ESR2 (0.65) | AKR1B10AKR1B1MEN1KMT2AAKR1A1 | |
| SCHEMBL32687713 | 0.76 | ESRRB (0.37) | ESRRBESRRAMEN1KMT2AGLA | |
| SCHEMBL10069265 | 0.73 | ADRA1A (0.35) | CA12CA1CA2CA9L3MBTL1 | |
| SCHEMBL13315793 | 0.73 | TDP1 (0.47) | CA12CA9MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745229-B2 | Chemoselective fluorgenic molecular linkers and methods for their preparation and use | UNIVERSITY OF SOUTH CAROLINA | 2010-06-29 | — | — | US | disclosed |
| US-20070224695-A1 | Chemoselective Fluorgenic Molecular Linkers and Methods for Their Preparation and Use | UNIVERSITY OF SOUTH CAROLINA (US) | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070224695-A1 | Chemoselective Fluorgenic Molecular Linkers and Methods for Their Preparation and Use | KIT, HLCS, ALK | CA12 283/4885CA1 558/4885CA2 824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.