Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | AGER | Q15109 | 3/20 | 0.48 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.48 |
| ▸ | FDPS | P14324 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16603976 | 0.77 | IDO1 (0.74) | APAF1MAPTPOLBIDO1CYP3A4 | |
| SCHEMBL3571485 | 0.72 | POLB (0.68) | APAF1MAPTPOLBCYP3A4CYP2D6 | |
| SCHEMBL11577563 | 0.71 | KDM4E (0.64) | APAF1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6854543 | 0.71 | APAF1 (0.52) | APAF1MAPTPOLBIDO1CYP3A4 | |
| SCHEMBL6854544 | 0.71 | APAF1 (0.52) | APAF1MAPTPOLBIDO1CYP3A4 | |
| SCHEMBL501835 | 0.70 | SMN1; SMN2 (0.60) | APAF1MAPTKMT2ALMNAHTT | |
| SCHEMBL2446284 | 0.70 | APAF1 (1.00) | APAF1MAPTPOLBCYP3A4CYP2D6 | |
| SCHEMBL13587954 | 0.69 | MAPT (0.66) | APAF1MAPTPOLBIDO1CYP3A4 | |
| SCHEMBL13316540 | 0.69 | TAS1R3 (0.35) | HTT | |
| SCHEMBL502119 | 0.69 | SMN1; SMN2 (0.59) | APAF1MAPTKMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728005-B2 | Ether derivative | AJINOMOTO CO., INC. (JP) | 2010-06-01 | — | — | US | disclosed |