Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | AGER | Q15109 | 1/20 | 0.55 |
| ▸ | APAF1 | O14727 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3575320 | 0.84 | POLB (0.57) | POLBKDM4EMAPTAGERAPAF1 | |
| SCHEMBL3585190 | 0.80 | SMN1; SMN2 (0.52) | KMT2AMAPK1SMN1; SMN2HTT | |
| SCHEMBL3566335 | 0.76 | SMN1; SMN2 (0.51) | POLBKDM4ELMNAALDH1A1KMT2A | |
| SCHEMBL3574069 | 0.75 | SMN1; SMN2 (0.53) | POLBKDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL3571488 | 0.74 | POLB (0.54) | POLBKDM4EMAPTAGERCYP2C9 | |
| SCHEMBL3580415 | 0.73 | KMT2A (0.52) | KDM4EKMT2AMAPK1SMN1; SMN2HTT | |
| SCHEMBL13316561 | 0.72 | APAF1 (0.53) | POLBKDM4EMAPTAGERAPAF1 | |
| SCHEMBL16603995 | 0.71 | AGER (1.00) | POLBMAPTAGERCYP3A4CYP2D6 | |
| SCHEMBL6855903 | 0.70 | MAPT (0.44) | POLBKDM4EMAPTAGERAPAF1 | |
| SCHEMBL3578459 | 0.70 | MEN1 (0.44) | MAPTLMNAALDH1A1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728005-B2 | Ether derivative | AJINOMOTO CO., INC. (JP) | 2010-06-01 | — | — | US | disclosed |
| US-20060270693-A1 | Ether derivative | AJINOMOTO CO., INC. (JP) | 2006-11-30 | — | — | US | disclosed |
| EP-1679296-A1 | ETHER DERIVATIVE | Ajinomoto Co., Inc. (JP) | 2006-07-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270693-A1 | Ether derivative | UROD, IL5, IL17A | POLB 2803/4885KDM4E 374/4885MAPT 694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.