Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL93209 | 0.77 | CHRM2 (0.40) | TSHRALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL29478286 | 0.74 | HTR2A (0.39) | TSHRCYP2C19MEN1KMT2AMAOA | |
| SCHEMBL5955814 | 0.74 | KDM1A (0.43) | TSHRALDH1A1NPSR1L3MBTL1CYP2C19 | |
| SCHEMBL17660056 | 0.74 | KDM1A (0.43) | TSHRALDH1A1NPSR1L3MBTL1CYP2C19 | |
| SCHEMBL18298261 | 0.74 | TSHR (0.39) | TSHRALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL3972334 | 0.74 | KDM1A (0.43) | TSHRALDH1A1NPSR1L3MBTL1CYP2C19 | |
| SCHEMBL7108506 | 0.70 | CHRM2 (0.49) | TSHRALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL10515985 | 0.70 | CHRNA7 (0.44) | TSHRALDH1A1MAPTNPSR1L3MBTL1 | |
| SCHEMBL3971547 | 0.70 | CHRM2 (0.49) | TSHRALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL7107611 | 0.67 | CHRM2 (0.40) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7737286-B2 | α-Hydroxy-benzeneacetic acid derivatives, and compounds having two 5-membered latone rings fused to central cyclohexa-1,4-diene nucleus based upon the same, and uses of the compounds | KYUNG-IN SYNTHETIC CORPORATION (KR) | 2010-06-15 | — | — | US | disclosed |
| US-20070220688-A1 | Alpha-Hydroxy-Benzeneacetic Acid Derivatives, and Compounds Having Two 5-Membered Latone Rings Fused to Central Cyclohexa-1,4-Diene Nucleus Based Upon the Same, and Uses of the Compounds | KYUNG-IN SYNTHETIC CORPORATION (KR) | 2007-09-27 | — | — | US | disclosed |
| US-20070220688-A1 | Alpha-Hydroxy-Benzeneacetic Acid Derivatives, and Compounds Having Two 5-Membered Latone Rings Fused to Central Cyclohexa-1,4-Diene Nucleus Based Upon the Same, and Uses of the Compounds | KYUNG-IN SYNTHETIC CORPORATION (KR) | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070220688-A1 | Alpha-Hydroxy-Benzeneacetic Acid Derivatives, and Compounds Having Two 5-Membered Latone Rings Fused to Central Cyclohexa-1,4-Diene Nucleus Based Upon the Same, and Uses of the Compounds | LDHA, HCAR1, HPD | TSHR 1927/4885ALDH1A1 280/4885LMNA 79/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.