Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 9/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | KDM1A | O60341 | 1/20 | 0.55 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | FLT1 | P17948 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.48 |
| ▸ | GBA1 | P04062 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201553 | 0.89 | KDM1A (0.66) | ABCG2MEN1KMT2AGAATGFBR1 | |
| SCHEMBL1062778 | 0.87 | TGFBR1 (0.71) | ABCG2MEN1KMT2AGAATGFBR1 | |
| SCHEMBL13319636 | 0.84 | ABCG2 (0.58) | ABCG2MEN1KMT2ATGFBR1MAPT | |
| SCHEMBL11920240 | 0.83 | ROCK2 (0.59) | ABCG2MEN1KMT2AGAATGFBR1 | |
| SCHEMBL16404312 | 0.82 | ABCG2 (0.72) | ABCG2MEN1KMT2AGAATGFBR1 | |
| SCHEMBL11920173 | 0.82 | ROCK2 (0.58) | ABCG2MEN1KMT2AGAATGFBR1 | |
| SCHEMBL22201341 | 0.81 | PRKD1 (0.66) | ABCG2MEN1KMT2ATGFBR1MAPT | |
| SCHEMBL22201354 | 0.79 | HPGD (0.55) | ABCG2TGFBR1MAPTSMN1; SMN2KDM1A | |
| SCHEMBL22201348 | 0.78 | PRKD1 (0.60) | ABCG2TGFBR1TP53MAPTSMN1; SMN2 | |
| SCHEMBL13319617 | 0.78 | MEN1 (0.65) | MEN1KMT2AGAATGFBR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8357693-B2 | Pharmacokinetically improved compounds | SURFACE LOGIX, INC. (US) | 2013-01-22 | — | — | US | disclosed |
| US-20100144707-A1 | Pharmacokinetically improved compounds | SURFACE LOGIX, LLC | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144707-A1 | Pharmacokinetically improved compounds | ROCK2, ROCK1, RHOT2 | ABCG2 280/4885MEN1 385/4885KMT2A 2324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.