Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 17/20 | 0.61 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.61 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | DRD2 | P14416 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.61 |
| ▸ | PGR | P06401 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10005269 | 0.93 | ADRB2 (0.62) | ADRB2ADRB1CYP3A4MAPK1ADRB3 | |
| SCHEMBL13898704 | 0.91 | ADRB2 (0.74) | ADRB2ADRB1CYP3A4MAPK1ADRB3 | |
| SCHEMBL13898911 | 0.90 | ADRB2 (0.59) | ADRB2ADRB1CYP3A4MAPK1ADRB3 | |
| SCHEMBL13897129 | 0.89 | CYP3A4 (0.59) | ADRB2ADRB1CYP3A4MAPK1ADRB3 | |
| SCHEMBL2672487 | 0.84 | ADRB2 (0.67) | ADRB2ADRB1CYP3A4MAPK1ADRB3 | |
| SCHEMBL10036716 | 0.83 | ADRB2 (0.79) | ADRB2ADRB1CYP3A4MAPK1ADRB3 | |
| SCHEMBL10665374 | 0.82 | ADRB2 (0.60) | ADRB2ADRB1CYP3A4MAPK1ADRB3 | |
| SCHEMBL13906283 | 0.82 | ADRB2 (0.74) | ADRB2ADRB1CYP3A4MAPK1ADRB3 | |
| SCHEMBL15159944 | 0.82 | ADRB2 (0.74) | ADRB2ADRB1CYP3A4MAPK1ADRB3 | |
| SCHEMBL16249283 | 0.82 | ADRB2 (0.74) | ADRB2ADRB1CYP3A4MAPK1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718822-B2 | Carbamate Stereoisomer | SEPRACOR INC. (US) | 2010-05-18 | — | — | US | disclosed |
| US-20090060917-A1 | Carbamate Stereoisomer | SEPRACOR INC. (US) | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090060917-A1 | Carbamate Stereoisomer | ADRB2, CHRM3, CHRM2 | ADRB2 1/4885ADRB1 4/4885CYP3A4 483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.