Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 16/20 | 0.79 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.79 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.79 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.79 |
| ▸ | TSHR | P16473 | 3/20 | 0.79 |
| ▸ | DRD2 | P14416 | 2/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.79 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.79 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.79 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.79 |
| ▸ | PGR | P06401 | 1/20 | 0.79 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.79 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.79 |
| ▸ | DRD3 | P35462 | 1/20 | 0.79 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4430362 | 0.92 | ADRB2 (0.80) | ADRB2ADRB1ADRB3CYP3A4MAPK1 | |
| SCHEMBL11819755 | 0.90 | ADRB2 (0.65) | ADRB2ADRB1ADRB3CYP3A4MAPK1 | |
| SCHEMBL11817913 | 0.90 | ADRB2 (0.77) | ADRB2ADRB1ADRB3CYP3A4MAPK1 | |
| Formoterol SCHEMBL15856256 | 0.88 | ADRB2 (1.00) | ADRB2ADRB1ADRB3CYP3A4MAPK1 | |
| Arformoterol SCHEMBL6547706 | 0.88 | ADRB2 (1.00) | ADRB2ADRB1ADRB3CYP3A4MAPK1 | |
| Arformoterol SCHEMBL117865 | 0.88 | ADRB2 (1.00) | ADRB2ADRB1ADRB3CYP3A4MAPK1 | |
| Arformoterol SCHEMBL4247 | 0.88 | ADRB2 (1.00) | ADRB2ADRB1ADRB3CYP3A4MAPK1 | |
| Arformoterol SCHEMBL458736 | 0.88 | ADRB2 (1.00) | ADRB2ADRB1ADRB3CYP3A4MAPK1 | |
| Arformoterol SCHEMBL3679114 | 0.88 | ADRB2 (1.00) | ADRB2ADRB1ADRB3CYP3A4MAPK1 | |
| Formoterol SCHEMBL6528975 | 0.88 | ADRB2 (1.00) | ADRB2ADRB1ADRB3CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9730890-B2 | Bronchodilating beta-agonist compositions and methods | MYLAN PHARMACEUTICALS, INC. (US) | 2017-08-15 | — | — | US | disclosed |
| US-20150209311-A1 | (R,R) FORMOTEROL IN COMBINATION WITH OTHER PHARMACOLOGICAL AGENTS | SUNOVION PHARMACEUTICALS INC. (US) | 2015-07-30 | — | — | US | disclosed |
| US-8623851-B2 | Formoterol/steroid bronchodilating compositions and methods of use thereof | MYLAN SPECIALTY L.P. (US) | 2014-01-07 | — | — | US | disclosed |
| US-8623922-B2 | Bronchodilating Beta-agonist compositions and methods | DEY PHARMA, L.P. (US) | 2014-01-07 | — | — | US | disclosed |
| US-20120309837-A1 | Bronchodilating Beta-Agonist Compositions and Methods | BANERJEE PARTHA S (US) | 2012-12-06 | — | — | US | disclosed |
| US-8114912-B2 | Bronchodilating β-agonist compositions and methods | MYLAN PHARMACEUTICALS, INC. (US) | 2012-02-14 | — | — | US | disclosed |
| US-20110166202-A1 | FORMOTEROL/STEROID BRONCHODILATING COMPOSITIONS AND METHODS OF USE THEREOF | DEY, L.P. (US) | 2011-07-07 | — | — | US | disclosed |
| US-20100240761-A1 | BRONCHODILATING BETA-AGONIST COMPOSITIONS AND METHODS | DEY, L.P. (US) | 2010-09-23 | — | — | US | disclosed |
| US-20100120734-A1 | FORMOTEROL/STEROID BRONCHODILATING COMPOSITIONS AND METHODS OF USE THEREOF | DEY, L.P. (US) | 2010-05-13 | — | — | US | disclosed |
| US-20100069342-A1 | FORMOTEROL/STEROID BRONCHODILATING COMPOSITIONS AND METHODS OF USE THEREOF | DEY, L.P. (US) | 2010-03-18 | — | — | US | disclosed |
| US-7465756-B2 | Bronchodilating beta-agonist compositions and methods | JPMORGAN CHASE BANK, N.A. (US) | 2008-12-16 | — | — | US | disclosed |
| US-7462645-B2 | Bronchodilating beta-agonist compositions and methods | JPMORGAN CHASE BANK, N.A. (US) | 2008-12-09 | — | — | US | disclosed |
| US-20080293788-A1 | Methods and Compositions for the Treatment of Pulmonary Diseases | SEPRACOR INC. | 2008-11-27 | — | — | US | disclosed |
| US-20080125461-A1 | (R,r)-Formoterol in Combination with Other Pharmacological Agents | SEPRACOR INC. (US) | 2008-05-29 | — | — | US | disclosed |
| US-7348362-B2 | Bronchodilating β-agonist compositions and methods | DEY, L.P. (US) | 2008-03-25 | — | — | US | disclosed |
| US-20070166235-A1 | BRONCHODILATING BETA-AGONIST COMPOSITIONS AND METHODS | DEY, L.P. (US) | 2007-07-19 | — | — | US | disclosed |
| US-20070166236-A1 | BRONCHODILATING BETA-AGONIST COMPOSITIONS AND METHODS | DEY, L.P. (US) | 2007-07-19 | — | — | US | disclosed |
| US-20070166240-A1 | BRONCHODILATING BETA-AGONIST COMPOSITIONS AND METHODS | DEY, L.P. (US) | 2007-07-19 | — | — | US | disclosed |
| US-20070160541-A1 | BRONCHODILATING BETA-AGONIST COMPOSITIONS AND METHODS | DEY, L.P. (US) | 2007-07-12 | — | — | US | disclosed |
| US-3994974-A | BRONCHODILATORS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1976-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166202-A1 | FORMOTEROL/STEROID BRONCHODILATING COMPOSITIONS AND METHODS OF USE THEREOF | ADRB2, CYP11B2, ADRB3 | ADRB2 1/4885ADRB1 4/4885ADRB3 3/4885 |
| US-20070166236-A1 | BRONCHODILATING BETA-AGONIST COMPOSITIONS AND METHODS | ADRB2, ADRB3, ADRB1 | ADRB2 1/4885ADRB1 3/4885ADRB3 2/4885 |
| US-20100240761-A1 | BRONCHODILATING BETA-AGONIST COMPOSITIONS AND METHODS | ADRB2, ADRB3, ADRB1 | ADRB2 1/4885ADRB1 3/4885ADRB3 2/4885 |
| US-20120309837-A1 | Bronchodilating Beta-Agonist Compositions and Methods | ADRB2, ADRB3, ADRB1 | ADRB2 1/4885ADRB1 3/4885ADRB3 2/4885 |
| US-20100120734-A1 | FORMOTEROL/STEROID BRONCHODILATING COMPOSITIONS AND METHODS OF USE THEREOF | ADRB2, CYP11B2, ADRB3 | ADRB2 1/4885ADRB1 4/4885ADRB3 3/4885 |
| US-20070160541-A1 | BRONCHODILATING BETA-AGONIST COMPOSITIONS AND METHODS | ADRB2, ADRB3, ADRB1 | ADRB2 1/4885ADRB1 3/4885ADRB3 2/4885 |
| US-20070166235-A1 | BRONCHODILATING BETA-AGONIST COMPOSITIONS AND METHODS | ADRB2, ADRB3, ADRB1 | ADRB2 1/4885ADRB1 3/4885ADRB3 2/4885 |
| US-20080293788-A1 | Methods and Compositions for the Treatment of Pulmonary Diseases | KCNN3, KCNN2, KCNN1 | ADRB2 164/4885ADRB1 178/4885ADRB3 163/4885 |
| US-20100069342-A1 | FORMOTEROL/STEROID BRONCHODILATING COMPOSITIONS AND METHODS OF USE THEREOF | ADRB2, CYP11B2, ADRB3 | ADRB2 1/4885ADRB1 4/4885ADRB3 3/4885 |
| US-20150209311-A1 | (R,R) FORMOTEROL IN COMBINATION WITH OTHER PHARMACOLOGICAL AGENTS | LTB4R, LTB4R2, TACR1 | ADRB2 15/4885ADRB1 22/4885ADRB3 39/4885 |
| US-20080125461-A1 | (R,r)-Formoterol in Combination with Other Pharmacological Agents | LTB4R, LTB4R2, CYSLTR1 | ADRB2 14/4885ADRB1 22/4885ADRB3 37/4885 |
| US-20070166240-A1 | BRONCHODILATING BETA-AGONIST COMPOSITIONS AND METHODS | ADRB2, ADRB3, ADRB1 | ADRB2 1/4885ADRB1 3/4885ADRB3 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.