Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 10/20 | 0.74 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.74 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.74 |
| ▸ | DRD2 | P14416 | 2/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.74 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.74 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.74 |
| ▸ | PGR | P06401 | 1/20 | 0.74 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.74 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.74 |
| ▸ | DRD3 | P35462 | 1/20 | 0.74 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30254890 | 1.00 | ADRB2 (0.74) | ADRB2ADRB3ADRB1DRD2CYP1A2 | |
| SCHEMBL13906283 | 1.00 | ADRB2 (0.74) | ADRB2ADRB3ADRB1DRD2CYP1A2 | |
| SCHEMBL15159944 | 1.00 | ADRB2 (0.74) | ADRB2ADRB3ADRB1DRD2CYP1A2 | |
| SCHEMBL1952781 | 0.93 | ADRB2 (0.66) | ADRB2ADRB3ADRB1DRD2CYP1A2 | |
| SCHEMBL13898704 | 0.92 | ADRB2 (0.74) | ADRB2ADRB3ADRB1DRD2CYP1A2 | |
| SCHEMBL10665374 | 0.90 | ADRB2 (0.60) | ADRB2ADRB3ADRB1DRD2CYP1A2 | |
| SCHEMBL20420611 | 0.89 | ADRB2 (0.64) | ADRB2ADRB3ADRB1DRD2CYP1A2 | |
| SCHEMBL3824204 | 0.89 | ADRB2 (0.64) | ADRB2ADRB3ADRB1DRD2CYP1A2 | |
| SCHEMBL13897129 | 0.88 | CYP3A4 (0.59) | ADRB2ADRB3ADRB1DRD2CYP1A2 | |
| SCHEMBL13906446 | 0.87 | ADRB2 (0.61) | ADRB2ADRB3ADRB1DRD2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9499475-B2 | Process for the preparation of arformoterol or salt thereof | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2016-11-22 | — | — | US | disclosed |
| US-9499475-B2 | Process for the preparation of arformoterol or salt thereof | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2016-11-22 | — | — | US | disclosed |
| US-20160083334-A1 | PROCESS FOR THE PREPARATION OF ARFORMOTEROL OR SALT THEREOF | GLENMARK LIFE SCIENCES LIMITED (IN) | 2016-03-24 | — | — | US | disclosed |
| US-20160083334-A1 | PROCESS FOR THE PREPARATION OF ARFORMOTEROL OR SALT THEREOF | GLENMARK LIFE SCIENCES LIMITED (IN) | 2016-03-24 | — | — | US | disclosed |
| WO-2014184756-A2 | PROCESS FOR THE PREPARATION OF ARFORMOTEROL OR SALT THEREOF | GLENMARK PHARMACEUTICALS LIMITED; GLENMARK GENERICS LIMITED (IN) | 2014-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160083334-A1 | PROCESS FOR THE PREPARATION OF ARFORMOTEROL OR SALT THEREOF | AGT, AGTR1, REN | ADRB2 8/4885ADRB3 14/4885ADRB1 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.