Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.80 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.62 |
| ▸ | ACHE | P22303 | 4/20 | 0.61 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.61 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.61 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.61 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.61 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.61 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.61 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.61 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dehydrostobadine SCHEMBL167500 | 0.90 | L3MBTL1 (0.97) | L3MBTL1SIRT2ACHEGRIN1GRIN2A | |
| Dehydrostobadine SCHEMBL29468212 | 0.90 | L3MBTL1 (0.97) | L3MBTL1SIRT2ACHEGRIN1GRIN2A | |
| Dehydrostobadine SCHEMBL3715610 | 0.89 | L3MBTL1 (1.00) | L3MBTL1SIRT2ACHEGRIN1GRIN2A | |
| Dehydrostobadine SCHEMBL2837548 | 0.89 | L3MBTL1 (1.00) | L3MBTL1SIRT2ACHEGRIN1GRIN2A | |
| SCHEMBL3238110 | 0.82 | L3MBTL1 (0.78) | L3MBTL1SIRT2ACHEGRIN1GRIN2A | |
| SCHEMBL10127681 | 0.82 | L3MBTL1 (0.82) | L3MBTL1SIRT2ACHEGRIN1GRIN2A | |
| SCHEMBL2186665 | 0.80 | L3MBTL1 (0.70) | L3MBTL1SIRT2ACHEGRIN1GRIN2A | |
| SCHEMBL12868029 | 0.79 | L3MBTL1 (0.73) | L3MBTL1SIRT2ACHEGRIN1GRIN2A | |
| SCHEMBL1120507 | 0.78 | L3MBTL1 (0.76) | L3MBTL1SIRT2ACHEGRIN1GRIN2A | |
| SCHEMBL15977201 | 0.78 | L3MBTL1 (0.76) | L3MBTL1SIRT2ACHEGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100125085-A1 | PYRIDOINDOLE MODULATORS OF NMDA RECEPTOR AND ACETYLCHOLINESTERASE | AUSPEX PHARMACEUTICALS, INC. (US) | 2010-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100125085-A1 | PYRIDOINDOLE MODULATORS OF NMDA RECEPTOR AND ACETYLCHOLINESTERASE | GRIN3A, GRIK5, CHRNA5 | L3MBTL1 3873/4885SIRT2 2988/4885ACHE 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.