Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | SRC | P12931 | 4/20 | 0.36 |
| ▸ | KDR | P35968 | 3/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | HCK | P08631 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.36 |
| ▸ | PRKDC | P78527 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13320352 | 0.92 | ALDH1A1 (0.45) | ALDH1A1ADORA2ABACE1CTSDKDM4E | |
| SCHEMBL4746018 | 0.91 | ALDH1A1 (0.44) | ALDH1A1NPC1POLBRAB9ADYRK1A | |
| SCHEMBL13320339 | 0.87 | CYP1A2 (0.39) | ALDH1A1NPC1POLBRAB9ASRC | |
| SCHEMBL4745812 | 0.83 | ALDH1A1 (0.34) | ALDH1A1ADORA2ASRCKDRPIK3CD | |
| SCHEMBL4746016 | 0.83 | HSP90AA1 (0.37) | ALDH1A1NPC1RAB9ADYRK1ASRC | |
| SCHEMBL4746019 | 0.82 | ALDH1A1 (0.44) | ALDH1A1ADORA2AMAPK14MEN1KMT2A | |
| SCHEMBL13320347 | 0.82 | CCR1 (0.39) | ALDH1A1KDRKDM4EMAPTMEN1 | |
| SCHEMBL13320354 | 0.82 | CA12 (0.37) | ALDH1A1KDR | |
| SCHEMBL4746389 | 0.82 | DHODH (0.34) | ALDH1A1NPC1RAB9AABL1BACE1 | |
| SCHEMBL13320366 | 0.81 | TDO2 (0.41) | ALDH1A1POLBSRCKDRPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431244-B2 | Indenochrysene derivative and organic light-emitting device using same | CANON KABUSHIKI KAISHA (JP) | 2013-04-30 | — | — | US | disclosed |
| US-8431244-B2 | Indenochrysene derivative and organic light-emitting device using same | CANON KABUSHIKI KAISHA (JP) | 2013-04-30 | — | — | US | disclosed |
| US-20100127618-A1 | INDENOCHRYSENE DERIVATIVE AND ORGANIC LIGHT-EMITTING DEVICE USING SAME | CANON KABUSHIKI KAISHA (JP) | 2010-05-27 | — | — | US | disclosed |
| US-20100127618-A1 | INDENOCHRYSENE DERIVATIVE AND ORGANIC LIGHT-EMITTING DEVICE USING SAME | CANON KABUSHIKI KAISHA (JP) | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100127618-A1 | INDENOCHRYSENE DERIVATIVE AND ORGANIC LIGHT-EMITTING DEVICE USING SAME | OR51E2, INTS9, ORAI2 | ALDH1A1 63/4885NPC1 2765/4885POLB 2587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.