SCHEMBL13320366

SCHEMBL13320366

Cc1ccc2c(c1)c(-c1ccc3ccncc3c1)cc1c3ccc(C)c4c3c(cc21)-c1ccccc1-4

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDO2 P48775 2/20 0.41
PIK3CD O00329 2/20 0.40
PIK3CB P42338 2/20 0.40
PIK3CG P48736 2/20 0.40
PRKCZ Q05513 1/20 0.37
KDR P35968 2/20 0.37
LCK P06239 1/20 0.37
CSF1R P07333 1/20 0.37
MAPK14 Q16539 1/20 0.37
ABL1 P00519 3/20 0.37
PRKCI P41743 1/20 0.36
KDM4E B2RXH2 4/20 0.35
ALDH1A1 P00352 3/20 0.35
MAPT P10636 3/20 0.35
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
RECQL P46063 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
CCNC P24863 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13320359 0.96 TDO2 (0.41) TDO2PIK3CDPIK3CBPIK3CGKDR
SCHEMBL4746063 0.88 PIK3CD (0.38) TDO2PIK3CDPIK3CBPIK3CGPRKCZ
SCHEMBL4746099 0.84 ABL1 (0.36) TDO2PIK3CDPIK3CBPIK3CGKDR
SCHEMBL13320362 0.83 TNF (0.41) KDRKDM4EALDH1A1MAPTKMT2A
SCHEMBL13320342 0.81 ALDH1A1 (0.45) PIK3CDPIK3CBPIK3CGKDRLCK
SCHEMBL13320352 0.81 ALDH1A1 (0.45) MAPK14KDM4EALDH1A1MAPTKMT2A
SCHEMBL4745812 0.79 ALDH1A1 (0.34) PIK3CDPIK3CBPIK3CGKDRABL1
SCHEMBL13320339 0.79 CYP1A2 (0.39) PIK3CDPIK3CBPIK3CGKDRABL1
SCHEMBL4746387 0.79 DHODH (0.33) KDM4EALDH1A1LMNA
SCHEMBL13320356 0.78 CYP11B1 (0.40) PRKCZKDRKDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8431244-B2 Indenochrysene derivative and organic light-emitting device using same CANON KABUSHIKI KAISHA (JP) 2013-04-30 US disclosed
US-8431244-B2 Indenochrysene derivative and organic light-emitting device using same CANON KABUSHIKI KAISHA (JP) 2013-04-30 US disclosed
US-20100127618-A1 INDENOCHRYSENE DERIVATIVE AND ORGANIC LIGHT-EMITTING DEVICE USING SAME CANON KABUSHIKI KAISHA (JP) 2010-05-27 US disclosed
US-20100127618-A1 INDENOCHRYSENE DERIVATIVE AND ORGANIC LIGHT-EMITTING DEVICE USING SAME CANON KABUSHIKI KAISHA (JP) 2010-05-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100127618-A1 INDENOCHRYSENE DERIVATIVE AND ORGANIC LIGHT-EMITTING DEVICE USING SAME OR51E2, INTS9, ORAI2 TDO2 34/4885PIK3CD 2352/4885PIK3CB 3428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.